在英國(guó),，腸癌被列為三大常見(jiàn)癌癥之一,，每年大概有3.5萬(wàn)人被診斷發(fā)現(xiàn)有腸癌，大約有1.6萬(wàn)人死于該疾病,。最近,，英國(guó)的癌癥研究機(jī)構(gòu)發(fā)現(xiàn)了2中基因缺陷和1/3的的腸癌有關(guān)。研究人員估計(jì),，每年大約有1.2萬(wàn)的腸癌患者通過(guò)基因修補(bǔ)能夠被治愈,。
生物谷專家表示，腸癌是僅次于肺癌的第二大人類殺手,，但是如果能被及早診斷,，治愈的機(jī)會(huì)還是比較的大。如果人們不注重運(yùn)動(dòng)和飲食,，腸癌的發(fā)病率相當(dāng)普通人來(lái)說(shuō)會(huì)較高,。腸癌患者一般都在55歲以上，但是近年來(lái),，腸癌發(fā)病有年輕化的趨勢(shì),。
英文原文：
Gene discovery could help treat bowel cancer
Two genetic defects that may be responsible for up to a third of bowel cancer cases have been discovered by scientists.
The breakthrough, signalled in a report published yesterday, could lead to a national screening programme for the disease, with those found to be at increased risk given specialised treatment.advertisementBowel cancer is the third most common cancer in Britain, with 35,000 people diagnosed with it every year, of which 16,000 die.
In the study, by Cancer Research UK's London research institute, scientists found two genetic defects which, when present with another defect that was discovered earlier this year, could be responsible for a up to a third of cases.
The report, published in the journal Nature Genetics yesterday, says that 12,000 people diagnosed with bowel cancer in Britain every year are likely to have this genetic make-up.
The researchers say that they are edging closer to being able to fully map the genetic codes that make people more likely to develop the disease.
Once this happens, they will be able to develop a blood test that could pinpoint those at greatest risk.
Bowel cancer is the second biggest cancer killer after lung cancer, but the illness is more easily treated if caught in the early stages.
Prof Ian Tomlinson, who led the research, said: "We're delighted to have taken our research forward to pin down the genes that influence a person's risk of developing bowel cancer.
"Increasing our understanding of genes like this may make it possible for scientists to eventually develop ways of stopping many people at increased risk of bowel cancer from developing the disease altogether."
Dr Lesley Walker, of Cancer Research UK, added: "Cancer Research UK is launching a series of genome-wide studies, including searches for genes that influence lung and ovarian cancer risk.
"Discoveries like this will improve our understanding of cancer and help us to develop targeted screening and treatment for people at increased risk of the disease.
"We hope that step by step we are coming closer to some form of screening.
"By identifying the genes responsible for the disease we would also be able to develop treatment specific to people with that genetic make-up."
Bowel cancer is also thought to be more common in people who lead an inactive lifestyle and who eat a diet rich in red meat. It largely affects people over the age of 55, but is increasingly common in younger patients.
