生物谷報道：子宮癌通常都是致命的,，因為它往往只有在晚期時才能發(fā)現(xiàn)出來。一項新研究表明狗能嗅出人類早期的子宮癌,。
科學家先前表明狗似乎能嗅出癌癥,。2004發(fā)表在《英國醫(yī)學雜志》上的一項研究成果發(fā)現(xiàn)狗通過嗅人類的尿液可以發(fā)現(xiàn)膀胱癌。2006年發(fā)表在《整合癌癥療法》雜志上的一項小規(guī)模的研究成果發(fā)現(xiàn),，經(jīng)過訓練的狗可以發(fā)現(xiàn)肺癌和乳癌,。而在此新研究中，研究人員訓練狗來識別不同類型和不同時期的子宮癌,。
研究人員發(fā)現(xiàn),，子宮癌的氣味似乎不同于其它婦科癌癥,，如宮頸癌和子宮內(nèi)膜癌。更重要的是,，早期和低級子宮癌發(fā)出的氣味和高級子宮癌的氣味一樣,。此研究成果發(fā)表在6月刊的《整合癌癥療法》（Integrative Cancer Therapies）雜志上。作者在文章中寫道：“我們的研究強有力地表明大多數(shù)普通子宮癌具有單種特殊的氣味,，經(jīng)過訓練的狗能識別出來,。不過，我們認為狗不會用于臨床應用中,，因為它們在工作期間容易受影響,，從而導致確診率發(fā)生變化。而且,，在受約束的環(huán)境下,，它們還是可以用于實驗應用中，以進一步探測這種有趣的新的癌癥診斷辦法,。”
相對人類而言,，狗鼻子的嗅覺細胞要敏感好幾倍。它們自然能嗅出炸彈,、毒品和埋藏的尸體,。事實上，動物有許多驚人的能力,，能感知人類不能察覺的事情,。
此項研究是由瑞典哥德堡醫(yī)學院的戈爾蓋·霍瓦斯博士負責?！墩习┌Y療法》雜志總編輯基思I.布魯克說：“我認為此項研究價值很大,，越來越多的人體研究表明這些經(jīng)過訓練的狗具有診斷本領(lǐng)。它們有能力可以發(fā)現(xiàn)與癌癥有關(guān)的特殊氣味,，最終將成為一種有效診斷早期癌癥的方法和工具,，因此將來的癌癥治愈比率將更高。”
子宮癌的死亡率是乳癌的3倍,。此外,，耶魯醫(yī)學院的研究人員今年2月進行的一項新血液檢測發(fā)現(xiàn)子宮癌的準確率達99%。目前正在對此方法進行臨床檢測,。（生物谷bioon.com）
生物谷推薦原始出處：
Integrative Cancer Therapies,，Vol. 7, No. 2, 76-80 (2008)，György Horvath, Gunvor af Klinteberg Järverud, Sven Järverud, and István Horváth
Human Ovarian Carcinomas Detected by Specific Odor
György Horvath
Department of Oncology, Sahlgrenska University Hospital, Göteborg, Sweden, [email protected]
Gunvor af Klinteberg Järverud
Department of Oncology, Swedish Working Dog Club, Kode, Sweden
Sven Järverud
Department of Oncology, Swedish Working Dog Club, Kode, Sweden
István Horváth
Department of Oncology, Hungarian Working Dog Club, Dunaszekcsö, Hungary
The high mortality rate associated with ovarian carcinoma is mainly owing to late diagnosis. It is thus essential to develop inexpensive and simple methods for early diagnosis. Papers on canine scent detection of malignancies such as melanoma and bladder, lung, and breast cancer have recently been published in peer-reviewed journals, indicating a new diagnostic tool for malignancies. However, in these studies the dogs may have responded to odors associated with cancer, such as inflammation or metabolic products, rather than specifically to cancer itself. Therefore, it is important to ascertain whether or not human cancers are characterized by specific odors. We hypothesized that if ovarian carcinoma emits a specific odor, dogs may be trained to detect it. Using our training method, we taught a dog to distinguish different histopathological types and grades of ovarian carcinomas, including borderline tumors, from healthy control samples. Double-blind tests showed 100% sensitivity and 97.5% specificity. Moreover, the odor of ovarian carcinomas seems to differ from those of other gynecological malignances such cervical, endometrial, and vulvar carcinomas. Our study strongly suggests that the most common ovarian carcinomas are characterized by a single specific odor.
