國一項(xiàng)最新研究顯示,常喝咖啡可降低患頭頸癌的風(fēng)險(xiǎn)。
頭頸癌包括口腔癌,、鼻癌、鼻竇癌,、唾液腺癌及淋巴癌等,。美國猶他州大學(xué)的研究人員在最新一期《癌癥流行病學(xué)、生物標(biāo)志與預(yù)防》雜志上報(bào)告說,,他們對國際頭頸癌流行病學(xué)聯(lián)合會提供的9項(xiàng)研究數(shù)據(jù)進(jìn)行分析后發(fā)現(xiàn),,常喝咖啡的人患口腔癌和咽喉癌的幾率要比不常喝咖啡的人低39%。如果每天喝4杯以上的咖啡,,這一效果會更加明顯,。
研究人員解釋說,咖啡中所含的抗氧化物等多種化學(xué)物質(zhì)可能是其有抗癌效果的原因之一,,但要了解其具體的抗癌機(jī)制還需更深入的研究,。此前美國和英國的研究曾顯示,常喝咖啡可降低前列腺癌,、神經(jīng)膠質(zhì)瘤和腦瘤等患病風(fēng)險(xiǎn),。(生物谷Bioon.net)
生物谷推薦最新腫瘤會議:第一屆上海腫瘤基礎(chǔ)和轉(zhuǎn)化醫(yī)學(xué)前沿研討會,2010
http://www.canceraisa.com/
生物谷推薦原文出處:
CEBP doi: 10.1158/1055-9965.EPI-10-0191
Coffee and Tea Intake and Risk of Head and Neck Cancer: Pooled Analysis in the International Head and Neck Cancer Epidemiology Consortium
Carlotta Galeone1,2, Alessandra Tavani1, Claudio Pelucchi1, Federica Turati1,2, Deborah M. Winn3, Fabio Levi4, Guo-Pei Yu5, Hal Morgenstern8, Karl Kelsey9, Luigino Dal Maso10, Mark P. Purdue3, Michael McClean11, Renato Talamini10, Richard B. Hayes6, Silvia Franceschi12, Stimson Schantz5, Zuo-Feng Zhang14, Gilles Ferro12, Shu-Chun Chuang15, Paolo Boffetta7,13, Carlo La Vecchia1,2 and Mia Hashibe12,16
Background: Only a few studies have explored the relation between coffee and tea intake and head and neck cancers, with inconsistent results.
Methods: We pooled individual-level data from nine case-control studies of head and neck cancers, including 5,139 cases and 9,028 controls. Logistic regression was used to estimate odds ratios (OR) and 95% confidence intervals (95% CI), adjusting for potential confounders.
Results: Caffeinated coffee intake was inversely related with the risk of cancer of the oral cavity and pharynx: the ORs were 0.96 (95% CI, 0.94–0.98) for an increment of 1 cup per day and 0.61 (95% CI, 0.47–0.80) in drinkers of >4 cups per day versus nondrinkers. This latter estimate was consistent for different anatomic sites (OR, 0.46; 95% CI, 0.30–0.71 for oral cavity; OR, 0.58; 95% CI, 0.41–0.82 for oropharynx/hypopharynx; and OR, 0.61; 95% CI, 0.37–1.01 for oral cavity/pharynx not otherwise specified) and across strata of selected covariates. No association of caffeinated coffee drinking was found with laryngeal cancer (OR, 0.96; 95% CI, 0.64–1.45 in drinkers of >4 cups per day versus nondrinkers). Data on decaffeinated coffee were too sparse for detailed analysis, but indicated no increased risk. Tea intake was not associated with head and neck cancer risk (OR, 0.99; 95% CI, 0.89–1.11 for drinkers versus nondrinkers).
Conclusions: This pooled analysis of case-control studies supports the hypothesis of an inverse association between caffeinated coffee drinking and risk of cancer of the oral cavity and pharynx.