美國研究人員最新研究發(fā)現(xiàn),大劑量攝入維生素D或可顯著降低罹患乳腺癌等疾病的風險,。
參與研究的加利福尼亞大學圣迭戈分校教授塞德里克·加蘭在一份新聞公報中說,,他們的研究發(fā)現(xiàn),成人每日攝入2000至4000國際單位(維生素D的1國際單位相當于0.025微克)維生素D可使血液中維生素D的代謝產(chǎn)物維持在一定水平,,從而顯著降低罹患一些疾病的風險,,包括乳腺癌、結腸癌,、多發(fā)性硬化癥和I型糖尿病等,。
研究人員說,他們對數(shù)千名每日服用1000至10000國際單位維生素D的成人進行調(diào)查,,得出上述結論,。參與調(diào)查期間,,被調(diào)查對象需要定期接受血液檢測,以確定他們血液中維生素D代謝產(chǎn)物的水平,。
根據(jù)美國國家衛(wèi)生研究院上世紀推薦的維生素D攝入標準,,50歲以下的人每日維生素D攝入量為200國際單位,51歲至70歲的人每日應攝入400國際單位,,而70歲以上的人每日應攝入600國際單位,。加蘭表示,他也驚訝于可有效預防癌癥的維生素D攝入量遠遠高于此前的推薦標準,。
目前,,研究人員對大劑量攝入維生素D是否會對身體產(chǎn)生副作用尚無定論。
相關研究成果發(fā)表在新一期《抗腫瘤研究》雜志上,。(生物谷Bioon.com)
生物谷推薦原文出處:
Anticancer Research, 2011; 31: 607-612
Vitamin D Supplement Doses and Serum 25-Hydroxyvitamin D in the Range Associated with Cancer Prevention
CEDRIC F. GARLAND, CHRISTINE B. FRENCH, LEO L. BAGGERLY, ROBERT P. HEANEY
Abstract
Abstract. Background: Studies indicate that intake of vitamin D in the range from 1,100 to 4,000 IU/d and a serum 25- hydroxyvitamin D concentration [25(OH)D] from 60-80 ng/ml may be needed to reduce cancer risk. Few community-based studies allow estimation of the dose–response relationship between oral intake of vitamin D and corresponding serum 25(OH)D in the range above 1,000 IU/d. Materials and Methods: A descriptive study of serum 25(OH)D concentration and self-reported vitamin D intake in a community-based cohort (n=3,667, mean age 51.3±13.4 y). Results: Serum 25(OH)D rose as a function of self-reported vitamin D supplement ingestion in a curvilinear fashion, with no intakes of 10,000 IU/d or lower producing 25(OH)D values above the lower-bound of the zone of potential toxicity (200 ng/ml). Unsupplemented all-source input was estimated at 3,300 IU/d. The supplemental dose ensuring that 97.5% of this population achieved a serum 25(OH)D of at least 40 ng/ml was 9,600 IU/d. Conclusion: Universal intake of up to 40,000 IU vitamin D per day is unlikely to result in vitamin D toxicity.