科學(xué)界一直在探尋日常飲食與癌癥的關(guān)聯(lián),。一項(xiàng)最新研究就顯示，常吃富含天然抗氧化劑硒和維生素C,、E的食物,，或許有助于降低人們患胰腺癌的風(fēng)險(xiǎn)。
英國(guó)東英吉利大學(xué)等機(jī)構(gòu)研究人員在新一期《內(nèi)臟》（Gut）雜志上發(fā)表報(bào)告說,，他們對(duì)2萬(wàn)多人進(jìn)行了跟蹤研究,，期間這些受調(diào)查者需要匯報(bào)他們的日常食物種類、分量以及采用何種烹飪方式等,。
分析顯示,，那些通過食物攝入硒等抗氧化劑物質(zhì)最多的受調(diào)查者，與攝入這類營(yíng)養(yǎng)物質(zhì)最少的那部分人相比,，患胰腺癌的風(fēng)險(xiǎn)要低67％,。這類營(yíng)養(yǎng)物質(zhì)常存在于谷類,、堅(jiān)果、水果和蔬菜等食物中,。
但研究人員也指出,，目前這項(xiàng)研究還只揭示了一種聯(lián)系，尚未完全證明其中的因果關(guān)系,。但據(jù)估算,，一旦證明胰腺癌風(fēng)險(xiǎn)的降低是由日常攝入食物的不同所導(dǎo)致，那么通過改變飲食習(xí)慣,，每12個(gè)胰腺癌病例中就有一個(gè)是可以避免的,。
領(lǐng)導(dǎo)這次研究的安德魯·哈特認(rèn)為，上述抗氧化劑起作用的機(jī)制可能包括：對(duì)吸煙等不良習(xí)慣導(dǎo)致的致癌物起到中和作用,，或是能促進(jìn)人體本身的免疫系統(tǒng)發(fā)揮抗癌作用,。(生物谷Bioon.com）
DOI：10.1136/gutjnl-2011-301908
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Dietary antioxidants and the aetiology of pancreatic cancer： a cohort study using data from food diaries and biomarkers
Objective To investigate whether the dietary antioxidants vitamins C and E， selenium and zinc decrease the risk of developing pancreatic cancer,， for the first time using 7-day food diaries,， the most accurate dietary methodology in prospective work. Design 23？658 participants,， aged 40–74,？years， recruited into the EPIC-Norfolk Study completed 7-day food diaries which recorded foods,， brands and portion sizes. Nutrient intakes were calculated in those later diagnosed with pancreatic cancer and in 3970 controls,， using a computer program with information on 11？000 foods. Vitamin C was measured in serum samples. The HRs of developing pancreatic cancer were estimated across quartiles of intake and thresholds of the lowest quartile (Q1) against a summation of the three highest (Q2–4). Results Within 10years,， 49 participants (55% men),， developed pancreatic cancer. Those eating a combination of the highest three quartiles of all of vitamins C and E and selenium had a decreased risk (HR=0.33， 95% CI 0.13 to 0.84,， p<0.05). There were threshold effects (Q2–4 vs Q1) for selenium (HR=0.49,， 95% CI 0.26 to 0.93， p<0.05) and vitamin E (HR=0.57,， 95% CI 0.29 to 1.09,， p<0.10). The HRs of quartiles for antioxidants， apart from zinc,， were <1,， but not statistically significant. For vitamin C， there was an inverse association with serum measurements (HR trend=0.67,， 95% CI 0.49 to 0.91,， p=0.01)， but the threshold effect from diaries was not significant (HR=0.68,， 95% CI 0.37 to 1.26). Conclusion The results support measuring antioxidants in studies investigating the aetiology of pancreatic cancer. If the association is causal,， 1 in 12 cancers might be prevented by avoiding the lowest intakes.
