法蘭德生物科技研究所和根特大學(xué)的科學(xué)家在新型抗線蟲作物培育方面邁進(jìn)了一步,。他們的研究表明,，線蟲能夠操控植物激素的運(yùn)輸，以迫使植物產(chǎn)生可供其食用的物質(zhì),。植物激素在植物生命周期中對多種生長和行為過程具有調(diào)控作用,，其中包括細(xì)胞分裂和伸長、韌皮部和木質(zhì)部分化以及根毛生長,。
在感染過程中,，線蟲向植物維管束細(xì)胞的某一部位注入多種蛋白。這些蛋白導(dǎo)致該細(xì)胞與周圍細(xì)胞融合,，并進(jìn)一步產(chǎn)生可供線蟲食用的物質(zhì)。植物激素在感染部位積累,，當(dāng)食用部位需要進(jìn)一步生長時,，相鄰細(xì)胞中植物激素的濃度便會增加。
Wim Grunewald及其同事的研究表明線蟲能破壞某些植物PIN蛋白的表達(dá),。而PIN蛋白能促進(jìn)細(xì)胞間的生長素傳遞,。利用該項(xiàng)發(fā)現(xiàn)可能會開發(fā)出阻止線蟲感染的各種方法，比如抵消線蟲對植物激素傳輸?shù)倪@種控制作用,。目前一般采用甲基溴來殺滅線蟲,，而這種殺蟲劑對環(huán)境具有嚴(yán)重的負(fù)面影響，因此在美國被禁止使用,。（生物谷Bioon.com）
生物谷推薦原始出處：
PLoS Pathog 5(1): e1000266. doi:10.1371/journal.ppat.1000266
Parasitic Nematodes Modulate PIN-Mediated Auxin Transport to Facilitate Infection
Wim Grunewald1,2*, Bernard Cannoot2, Ji?í Friml1, Godelieve Gheysen2
1 Department of Plant Systems Biology, Ghent University, Ghent, Belgium, 2 Department of Molecular Biotechnology, Ghent University, Ghent, Belgium
Abstract
Plant-parasitic nematodes are destructive plant pathogens that cause significant yield losses. They induce highly specialized feeding sites (NFS) in infected plant roots from which they withdraw nutrients. In order to establish these NFS, it is thought that the nematodes manipulate the molecular and physiological pathways of their hosts. Evidence is accumulating that the plant signalling molecule auxin is involved in the initiation and development of the feeding sites of sedentary plant-parasitic nematodes. Intercellular transport of auxin is essential for various aspects of plant growth and development. Here, we analysed the spatial and temporal expression of PIN auxin transporters during the early events of NFS establishment using promoter-GUS/GFP fusion lines. Additionally, single and double pin mutants were used in infection studies to analyse the role of the different PIN proteins during cyst nematode infection. Based on our results, we postulate a model in which PIN1-mediated auxin transport is needed to deliver auxin to the initial syncytial cell, whereas PIN3 and PIN4 distribute the accumulated auxin laterally and are involved in the radial expansion of the NFS. Our data demonstrate that cyst nematodes are able to hijack the auxin distribution network in order to facilitate the infection process.
