很多時候，當(dāng)婚姻出現(xiàn)問題時,，人們會把責(zé)任怪罪在男方頭上,，認(rèn)為男士的花心導(dǎo)致了婚姻破裂。
然而,，在近期的Biological Psychiatry雜志上刊登的一項(xiàng)研究成果表明,，據(jù)瑞典斯德哥爾摩卡羅林斯卡醫(yī)學(xué)院的最新研究發(fā)現(xiàn)，婚姻出現(xiàn)破裂也有可能是女性體內(nèi)攜帶的一種基因作祟所致,。一種叫A-allele的催產(chǎn)素受體基因會在女性體內(nèi)搞怪,，讓女性對婚姻關(guān)系中偶爾出現(xiàn)的不和諧插曲缺乏耐心，脾氣暴躁,，從而提高離婚率,。
女性處于生產(chǎn)期和哺乳期時體內(nèi)會自行分泌催產(chǎn)素，這種激素能拉近女性和后代間的關(guān)系。不過若催產(chǎn)素分泌異常就會攪亂大腦對感情問題的處理能力,，催生叫A-allele的“離婚基因”,。研究人員調(diào)查了1800名女性后發(fā)現(xiàn)攜帶這種基因的女性離婚率高50%。(生物谷 Bioon.com)
doi:10.1016/j.biopsych.2011.09.002
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Variation in the Oxytocin Receptor Gene Is Associated with Pair-Bonding and Social Behavior
Hasse Walum , Paul Lichtenstein, Jenae M. Neiderhiser, David Reiss, Jody M. Ganiban, Erica L. Spotts, Nancy L. Pedersen, Henrik Anckarsäterb, Henrik Larsson, Lars Westberg
Background
In specific vole and primate species the neuropeptide oxytocin plays a central role in the regulation of pair-bonding behavior. Here we investigate the extent to which genetic variants in the oxytocin receptor gene (OXTR) are associated with pair-bonding and related social behaviors in humans.
Methods
We first genotyped twelve single nucleotide polymorphisms (SNPs) in the TOSS (Twin and Offspring Study in Sweden) (n = 2309) and the TCHAD (Swedish Twin Study of Child and Adolescent Development) (n = 1240), comprising measures of self-reported pair-bonding behavior. In the TOSS sample we further investigated one of the SNPs for measures of marital status and quality. Moreover, in the TCHAD sample we explored the longitudinal relationship between precursors of pair-bonding during childhood and subsequent behavior in romantic relationships. Finally, in the TCHAD study and in the Child and Adolescent Twin Study of Sweden (CATSS) (n = 1771), the association between the same SNP and childhood behaviors was investigated.
Results
One SNP (rs7632287) in OXTR was associated with traits reflecting pair-bonding in women in the TOSS and TCHAD samples. In girls the rs7632287 SNP was further associated with childhood social problems, which longitudinally predicted pair-bonding behavior in the TCHAD sample. This association was replicated in the CATSS sample in which an association between the same SNP and social interaction deficit symptoms from the autism spectrum was detected.
Conclusion
These results suggest an association between variation in OXTR and human pair-bonding and other social behaviors, possibly indicating that the well-described influence of oxytocin on affiliative behavior in voles could also be of importance for humans.
