生物谷報(bào)道：英美科學(xué)家在6月5日的《科學(xué)》（Science）雜志發(fā)表論文稱5-羥色胺在我們選擇性地保持情緒控制上扮演著一個(gè)關(guān)鍵性的角色。
當(dāng)有人沒有像他們自己希望被對(duì)待的方式善待你的時(shí)候（即他們觸犯了公平的黃金法則的時(shí)候），你是否曾經(jīng)想發(fā)火,？如果你設(shè)法控制住了自己的情緒并按捺住了進(jìn)攻性的沖動(dòng),，你應(yīng)該感謝你大腦中的化學(xué)物質(zhì)5-羥色胺,。在玩一種“最后通牒游戲”的時(shí)候,，那些體內(nèi)5-羥色胺水平被損耗的人會(huì)更加容易地拒絕不公正提議,，即使當(dāng)時(shí)他們報(bào)告說并沒有情緒不穩(wěn)定或其它的可能會(huì)影響他們選擇的能力損害,。這種游戲現(xiàn)在已經(jīng)被神經(jīng)科學(xué)家和心理學(xué)家廣泛應(yīng)用,，它的玩法是由一位玩家提出一種方法與另外一位玩家來分一罐錢,。如果提議被接受的話，兩位玩家都會(huì)得到薪酬,。如果提議被拒絕的話,，這兩位玩家都不會(huì)賺取任何錢,，這使得報(bào)復(fù)行為的代價(jià)很高。
在一項(xiàng)研究調(diào)查中,，20位自愿者或是得到一顆安慰劑或是一顆能降低5-羥色胺的藥物,，然后再由他們接受或拒絕別人的提議,。那些服用5-羥色胺阻斷劑的人會(huì)更容易地拒絕不公正的提議,。這些結(jié)果來自首次應(yīng)用最后通牒游戲所作的基于生物化學(xué)的研究。（生物谷www.bioon.com）
生物谷推薦原始出處：
Science,，DOI: 10.1126/science.1155577,，Molly J. Crockett，Trevor W. Robbins
Serotonin Modulates Behavioral Reactions to Unfairness
Molly J. Crockett 1*, Luke Clark 1, Golnaz Tabibnia 2, Matthew D. Lieberman 2, Trevor W. Robbins 1
1 Department of Experimental Psychology, University of Cambridge, UK.; Behavioural and Clinical Neuroscience Institute, University of Cambridge, UK.
2 Department of Psychology, University of California Los Angeles, USA.
* To whom correspondence should be addressed.
Molly J. Crockett , E-mail: [email protected]
Serotonin (5-HT) has long been implicated in social behavior and impulsivity, but the mechanisms through which it modulates self-control remain unclear. We observed the effects of manipulating 5-HT function on behavior in the Ultimatum Game, where players must decide whether to accept or reject fair or unfair monetary offers from another player. Participants with depleted 5-HT levels rejected a greater proportion of unfair, but not fair offers, without showing changes in mood, fairness judgments, basic reward processing, or response inhibition. Our results suggest that 5-HT plays a critical role in regulating emotion during social decision-making.
