英國(guó)《BMC生理學(xué)》雜志刊登的一項(xiàng)最新研究顯示，吸入汽油煙霧會(huì)影響實(shí)驗(yàn)鼠的神經(jīng)系統(tǒng),，使其變得更具攻擊性,。
埃及開(kāi)羅大學(xué)研究人員在《BMC生理學(xué)》雜志上報(bào)告說(shuō)，他們將實(shí)驗(yàn)鼠分為3組,，分別處于無(wú)鉛汽油煙霧,、含鉛汽油煙霧或清潔空氣環(huán)境中，結(jié)果顯示,，與處于清潔空氣環(huán)境中的實(shí)驗(yàn)鼠相比,，兩組暴露在汽油煙霧下的實(shí)驗(yàn)鼠出現(xiàn)更多攻擊行為。
對(duì)這些實(shí)驗(yàn)鼠大腦的檢查顯示,，實(shí)驗(yàn)鼠吸入的汽油分子會(huì)導(dǎo)致其大腦中的神經(jīng)遞質(zhì)水平出現(xiàn)明顯波動(dòng),，這可能是它們更具攻擊性的原因。
研究人員說(shuō),，汽車(chē)尾氣等中還有大量汽油分子,，他們的研究成果或許可以幫助解釋一些開(kāi)車(chē)人為何常變得煩躁，因此他們建議公共衛(wèi)生部門(mén)更多關(guān)注這方面的研究,。（生物谷Bioon.com）
生物谷推薦原始出處：
BMC Physiology 2009, 9:21doi:10.1186/1472-6793-9-21
Impact of gasoline inhalation on some neurobehavioural characteristics of male rats
Background
This paper examines closely and compares the potential hazards of inhalation of two types of gasoline (car fuel). The first type is the commonly use leaded gasoline and the second is the unleaded type enriched with oxygenate additives as lead substituent in order to raise the octane number. The impacts of gasoline exposure on Na+, K+-ATPase, superoxide dismutase (SOD), acetylcholinesterase (AChE), total protein, reduced glutathione (GSH), and lipid peroxidation (TBARS) in the cerebral cortex, and monoamine neurotransmitters dopamine (DA), norepinephrine (NE) and serotonin (5-HT) in the cerebral cortex, hippocampus, cerebellum and hypothalamus were evaluated. The effect of gasoline exposure on the aggressive behaviour tests was also studied.
Results
The present results revealed that gasoline inhalation induced significant fluctuations in the levels of the monoamine neurotransmitters in the studied brain regions. This was concomitant with a decrease in Na+, K+-ATPase activity and total protein content. Moreover, the group exposed to the unleaded gasoline exhibited an increase in lipid peroxidation and a decrease in AChE and superoxide dismutase activities. These physiological impairments were accompanied with a higher tendency towards aggressive behaviour as a consequence to gasoline inhalation.
Conclusion
It is concluded from the present work that chronic exposure to either the leaded or the unleaded gasoline vapours impaired the levels of monoamine neurotransmitters and other biochemical parameters in different brain areas and modulated several behavioural aspects related to aggression in rats.
