生物谷Bioon.com 訊 北京師范大學(xué)認(rèn)知神經(jīng)科學(xué)與學(xué)習(xí)研究所Gui Xue（第一作者）等研究人員最新研究結(jié)果發(fā)表于Science上,。該結(jié)果證明記憶力在相同的神經(jīng)性表現(xiàn)被再次激活時(shí)（而不是在激活模式顯得不同的時(shí)候）會(huì)更容易地保留在一個(gè)人的頭腦中,。這一發(fā)現(xiàn)為心理學(xué)界的一個(gè)長(zhǎng)期存在的爭(zhēng)論提供了答案。
當(dāng)人在研究某東西或試圖將其銘記住的時(shí)候,，他們會(huì)產(chǎn)生不同的神經(jīng)活動(dòng)模式,。 如今，研究人員說(shuō),，在這一記憶編碼時(shí)期的類似的神經(jīng)活動(dòng)模式實(shí)際上表明該個(gè)人在以后某個(gè)日子會(huì)有較大的可能性回想起該段記憶,。 研究人員說(shuō)，那些看來(lái)不相同的神經(jīng)活動(dòng)模式被人們記住的可能性不大,。 為了做出這一發(fā)現(xiàn),，Gui Xue及其同事用功能性核磁共振成像（fMRI）對(duì)健康志愿者的腦進(jìn)行了監(jiān)控，在監(jiān)控的時(shí)候,，這些志愿者正在從事一組實(shí)驗(yàn),。 例如，在某個(gè)試驗(yàn)中,，這些志愿者試圖記住120個(gè)不同的人臉,，其中每張臉會(huì)在4個(gè)不同的時(shí)間被展示給他們看,。1小時(shí)后，研究人員向這些志愿者展示了240張臉,，其中有一半是他們已經(jīng)看到過(guò)的,，有一半則是新的面孔。研究人員讓這些志愿者找出哪些面孔是他們過(guò)去曾經(jīng)見(jiàn)到過(guò)的,。 （生物谷Bioon.com）
生物谷推薦英文摘要：
Science DOI: 10.1126/science.1193125
Greater Neural Pattern Similarity Across Repetitions Is Associated with Better Memory
Gui Xue,1,2 Qi Dong,1,* Chuansheng Chen,3 Zhonglin Lu,2 Jeanette A. Mumford,4 Russell A. Poldrack5,4,6,*
Repeated study improves memory, but the underlying neural mechanisms of this improvement are not well understood. Using functional magnetic resonance imaging and representational similarity analysis of brain activity, we found that, compared with forgotten items, subsequently remembered faces and words showed greater similarity in neural activation across multiple study in many brain regions, including (but not limited to) the regions whose mean activities were correlated with subsequent memory. This result addresses a longstanding debate in the study of memory by showing that successful episodic memory encoding occurs when the same neural representations are more precisely reactivated across study episodes, rather than when patterns of activation are more variable across time.
1 State Key Laboratory of Cognitive Neuroscience and Learning, Beijing Normal University, Beijing 100875, China.
2 Department of Psychology, University of Southern California, Los Angeles, CA 90089, USA.
3 Department of Psychology and Social Behavior, University of California, Irvine, CA 92697, USA.
4 Departments of Psychology, University of Texas, Austin, TX 78759, USA.
5 Imaging Research Center, University of Texas, Austin, TX 78759, USA.
6 Departments of Neurobiology, University of Texas, Austin, TX 78759, USA
