母總是提醒我們要勤洗手,,而洗得太干凈真的對(duì)我們的健康有好處嗎,?據(jù)美國(guó)“每日科學(xué)”近日?qǐng)?bào)道,美國(guó)最新研究發(fā)現(xiàn),,抗菌香皂中含有一種名為“三氯生”的化學(xué)物質(zhì),,過多使用抗菌香皂會(huì)增加青少年罹患過敏性疾病的風(fēng)險(xiǎn),并損害成年人的免疫系統(tǒng),。
密歇根大學(xué)公共衛(wèi)生學(xué)院副教授艾洛表示:“這項(xiàng)研究發(fā)現(xiàn)支持了衛(wèi)生假設(shè)理論,,該理論認(rèn)為生活在非常清潔衛(wèi)生的環(huán)境中減少了我們接觸微生物的機(jī)會(huì),而這可能會(huì)影響人體免疫系統(tǒng)的正常發(fā)育,。換言之,,太愛干凈反而更容易讓我們生病。”(生物谷Bioon.com)
生物谷推薦原文出處:
Environmental Health Perspectives DOI: 10.1289/ehp.1002883
The Impact of Bisphenol A and Triclosan on Immune Parameters in the US Population, NHANES 2003-2006
Erin M. Rees Clayton, Megan Todd, Jennifer Beam Dowd, Allison E. Aiello
Background: Exposure to environmental toxicants is associated with numerous disease outcomes, many of which involve underlying immune and inflammatory dysfunction.
Objectives: To address the gap between environmental exposures and immune dysfunction, we investigated the association of two endocrine-disrupting compounds with markers of immune function.
Methods: Using data from the 2003-2006 National Health and Nutrition Examination Survey, we compared urinary bisphenol A (BPA) and triclosan with serum cytomegalovirus antibody levels and diagnosis of allergies or hayfever in US adults and children age ≥ 6 years. We used multivariate ordinary least squares linear regression models to examine the association of BPA and triclosan with cytomegalovirus antibody titers, and multivariate logistic regression models to investigate the association of these chemicals with allergy/hayfever diagnosis. Statistical models were stratified by age (<18 years and ≥18 years).
Results: In analyses adjusted for age, sex, race, BMI, creatinine levels, family income, and educational attainment, in the ≥18 age group, higher urinary BPA levels were associated with higher cytomegalovirus antibody titers (p<0.001). In the <18 age group, lower levels of BPA were associated with higher cytomegalovirus antibody titers (p<0.05). However, triclosan, but not BPA, showed a positive association with allergy/hayfever diagnosis. In the under 18 age group, higher levels of triclosan were associated with greater odds of having been diagnosed with allergies or hayfever (p<0.01).
Conclusions: Endocrine-disrupting chemicals like BPA and triclosan may negatively impact human immune function as measured by CMV antibody levels and allergy/hayfever diagnosis, respectively, with differential consequences based on age. Additional studies should be done to investigate these findings.