飲酒有助預(yù)防關(guān)節(jié)炎是不少人的經(jīng)驗(yàn)之談,,一項(xiàng)最新科學(xué)研究再次證實(shí)了這種說法的合理性,,這項(xiàng)研究發(fā)現(xiàn)那些適度飲酒的人與不飲酒的人相比患風(fēng)濕性關(guān)節(jié)炎的風(fēng)險(xiǎn)的確更低。新一期《英國醫(yī)學(xué)雜志》(British Medical Journal )刊登了這項(xiàng)報(bào)告,。
瑞典卡羅琳醫(yī)學(xué)院等機(jī)構(gòu)研究人員調(diào)查了3萬多名女性的健康資料,,她們出生于1914年到1948年之間,接受了長期的跟蹤調(diào)查,,其中有些人一直被跟蹤到2009年,。
分析顯示,那些每個(gè)星期飲酒量在3杯以上者,,與不飲酒者相比患風(fēng)濕性關(guān)節(jié)炎的風(fēng)險(xiǎn)要低52%,;而每周飲酒4杯以上者,與每周飲酒不到1杯者相比患風(fēng)濕性關(guān)節(jié)炎的風(fēng)險(xiǎn)也要低37%,。這里對一杯酒的定義是相當(dāng)于含15克酒精,,對飲用紅酒、啤酒等各種情況都進(jìn)行了折算,,這些不同的酒類在預(yù)防關(guān)節(jié)炎方面都有相似的效果,。
研究人員說,關(guān)節(jié)炎是由免疫系統(tǒng)錯(cuò)誤地攻擊關(guān)節(jié)部位的健康組織引起,,而酒精可以抑制免疫系統(tǒng)的這種作用,,因此飲酒有助預(yù)防關(guān)節(jié)炎。
對于酒精的這種作用,,近年來逐漸有研究予以揭示,,比如2006年瑞典哥德堡大學(xué)研究人員在美國《國家科學(xué)院院刊》上報(bào)告說,如果讓實(shí)驗(yàn)鼠每日攝入少量酒精,,能夠明顯降低它們患風(fēng)濕性關(guān)節(jié)炎的風(fēng)險(xiǎn),;2010年,英國設(shè)菲爾德大學(xué)研究人員也在《風(fēng)濕病學(xué)》雜志上報(bào)告說,,對一些關(guān)節(jié)炎患者的調(diào)查顯示,,飲酒可以減輕他們的關(guān)節(jié)炎癥狀。
不過研究人員也強(qiáng)調(diào)說,,飲酒有助預(yù)防關(guān)節(jié)炎并不能成為酗酒的借口,,因?yàn)樵缬醒芯匡@示酗酒會(huì)導(dǎo)致多方面的健康風(fēng)險(xiǎn),只有適度的飲酒,,才能對酒精用其利而避其弊,。(生物谷Bioon.com)
doi:10.1136/bmj.e4230
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Long term alcohol intake and risk of rheumatoid arthritis in women: a population based cohort study
Di Giuseppe, Daniela; Alfredsson, Lars; Bottai, Matteo; Askling, Johan; Wolk, Alicja
Objective To analyse the association between alcohol intake and incidence of rheumatoid arthritis in women. Design Prospective cohort study with repeated measurements. Setting The Swedish Mammography Cohort, a population based cohort from central Sweden. Participants 34?141 women born between 1914 and 1948, followed up from 1 January 2003 to 31 December 2009. Main outcome measures Newly diagnosed cases of rheumatoid arthritis identified by linkage with two Swedish national registers. Data on alcohol consumption were collected in 1987 and 1997. Results During the follow-up period (226?032 person years), 197 incident cases of rheumatoid arthritis were identified. There was a statistically significant 37% decrease in risk of rheumatoid arthritis among women who drank >4 glasses of alcohol (1 glass = 15 g of ethanol) per week compared with women who drank <1 glass per week or who never drank alcohol (relative risk 0.63 (95% confidence interval 0.42 to 0.96), P=0.04). Drinking of all types of alcohol (beer, wine, and liquor) was non-significantly inversely associated with the risk of rheumatoid arthritis. Analysis of long term alcohol consumption showed that women who reported drinking >3 glasses of alcohol per week in both 1987 and 1997 had a 52% decreased risk of rheumatoid arthritis compared with those who never drank (relative risk 0.48 (0.24 to 0.98)). Conclusion Moderate consumption of alcohol is associated with reduced risk of rheumatoid arthritis.