生物谷報道：人類以前對食肉菌的認(rèn)識很少,，本周Science上報道的這篇研究揭示了食肉菌是如何進(jìn)入獵物體內(nèi),，然后殺死獵物,，最終分解各種水解酶將肉類分解的過程的機(jī)理。
A Predator Unmasked: Life Cycle of Bdellovibrio bacteriovorus from a Genomic Perspective
Snjezana Rendulic,1 Pratik Jagtap,1* Andrea Rosinus,1* Mark Eppinger,1* Claudia Baar,1* Christa Lanz,1 Heike Keller,1 Carey Lambert,2 Katy J. Evans,2 Alexander Goesmann,3 Folker Meyer,3 R. Elizabeth Sockett,2 Stephan C. Schuster1
Predatory bacteria remain molecularly enigmatic, despite their presence in many microbial communities. Here we report the complete genome of Bdellovibrio bacteriovorus HD100, a predatory Gram-negative bacterium that invades and consumes other Gram-negative bacteria. Its surprisingly large genome shows no evidence of recent gene transfer from its prey. A plethora of paralogous gene families coding for enzymes, such as hydrolases and transporters, are used throughout the life cycle of B. bacteriovorus for prey entry, prey killing, and the uptake of complex molecules.
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