瑞典醫(yī)學(xué)研究人員的最新研究成果顯示,，乳腺炎與乳腺癌并沒有多大的直接關(guān)聯(lián),。
瑞典卡羅林斯卡醫(yī)學(xué)院和瑞典烏普薩拉地區(qū)腫瘤防治中心的研究人員近期對8000多名因患嚴(yán)重乳腺炎而住院治療的婦女進(jìn)行了跟蹤調(diào)查,。他們發(fā)現(xiàn),，被調(diào)查婦女中后來有106人患上了乳腺癌,，不過在這些乳腺癌患者中發(fā)生癌變的乳房只有一半曾患過乳腺炎,。研究人員因此認(rèn)為,，乳腺炎與乳腺癌并沒有多大的直接關(guān)聯(lián),，乳腺炎直接誘發(fā)乳腺癌的危險性并不大。
根據(jù)哺乳有助于預(yù)防乳腺癌的理論,，研究人員還認(rèn)為,，得過乳腺炎的婦女之所以容易患上乳腺癌，主要是因為她們在得了乳腺炎后提前中斷了哺乳,。
乳腺炎是指乳腺的急性化膿性感染,，是產(chǎn)褥期的常見病，迄今其病因尚無權(quán)威解釋。瑞典研究人員的上述研究成果發(fā)表在9月一期的《流行病學(xué)》（Epidemiology）期刊上,。（生物谷Bioon.com）
生物谷推薦原始出處：
Epidemiology:doi: 10.1097/EDE.0b013e3181adbb1e
Mastitis and the Risk of Breast Cancer
Lambe, Mats; Johansson, Anna L. V.; Altman, Daniel; Eloranta, Sandra
Background: Many cancers arise from sites of infection and inflammation. Results from animal studies indicate that inflammatory cells may facilitate neoplastic processes by orchestrating the tumor microenvironment. Little is known about the role of inflammation in the etiology of breast cancer. The aim of this study was to examine possible associations between a history of mastitis requiring hospitalization and subsequent risk of breast cancer.
Methods: This cohort study of 2,577,565 women used data from several Swedish population-based registers, including the Inpatient Register and the Cancer Register. The risk of breast cancer was assessed by Poisson regression modeling.
Results: We identified 8411 women in the Inpatient Register with a discharge diagnosis of mastitis. Of these, 106 had a subsequent diagnosis of breast cancer recorded in the Cancer Register. Compared with women who had no recorded mastitis, the incidence rate of breast cancer (regardless of laterality) was higher in women with mastitis, with an incidence rate ratio of 1.23 (95% confidence interval [CI] = 1.02-1.49) following adjustment for age, calendar time, age at first birth and parity. In the group of women among whom information on laterality was available for both the mastitis and the malignancy (n = 87), side of lesions corresponded for 52% (95% CI = 41%-62%), which is what could be expected by chance.
Conclusions: The overall risk of breast cancer was slightly elevated in women with a history of mastitis recorded in the Inpatient Register. The absence of a correlation between laterality of lesions, however, does not support a causal association between inflammation and the development of breast cancer.
