一項新的研究表明阿司匹林和其他類似的止痛藥可能有助于防止皮膚癌,。相關(guān)研究論文發(fā)表在Cancer雜志上,。
以往研究表明服用非類固醇消炎藥物或NSAIDs，其中包括阿司匹林,、布洛芬,、萘普生以及各種其他的非處方藥和處方藥，可以減少患某些類型癌癥的風(fēng)險,。丹麥奧胡斯大學(xué)醫(yī)院的研究證實這些藥物可能會降低三個主要類型的皮膚癌的風(fēng)險：基底細(xì)胞癌,、鱗狀細(xì)胞癌以及惡性黑色素瘤。
研究人員分析了從1991年到2009年間,，丹麥北部地區(qū)就診患者,，有1974例鱗狀細(xì)胞癌，13316例基底細(xì)胞癌和3242例惡性黑色素瘤被診斷,。他們比較了皮膚癌患者與178655名未患皮膚癌患者的信息包括處方數(shù)據(jù)。
那些服用兩種以上非甾體抗炎藥的人患鱗狀細(xì)胞癌的風(fēng)險下降15％,，患惡性黑色素瘤的風(fēng)險下降13％,，相比于使用兩種或更少的處方藥物的患者。尤其是當(dāng)服用非甾體抗炎藥時間超過7年或是服用頻率較高的人患皮膚癌的風(fēng)險下降越明顯,。
我們希望非甾體抗炎藥預(yù)防癌癥的效果會引發(fā)更多有關(guān)預(yù)防皮膚癌的研究,。此外，這種潛在的預(yù)防癌癥的效果應(yīng)當(dāng)權(quán)衡NSAID的好處和危害,。（生物谷：Bioon.com）
doi:10.1002/cncr.27406
PMC:
PMID:
Nonsteroidal anti-inflammatory drugs and the risk of skin cancer: A population-based case-control study
Sigrún Alba Jóhannesdóttir, Ellen T. Chang, Frank Mehnert, Morten Schmidt, Anne Braae Olesen, Henrik Toft Sørensen.
Previous studies suggest that taking nonsteroidal anti-inflammatory drugs, or NSAIDs, which include aspirin, ibuprofen, and naproxen, as well as a variety of other nonprescription and prescription drugs, can decrease an individual's risk of developing some types of cancer. Sigrún Alba Jóhannesdóttir, BSc, of Aarhus University Hospital in Denmark, and her colleagues looked to see if the medications might decrease the risk of the three major types of skin cancer: basal cell carcinoma, squamous cell carcinoma, and malignant melanoma.The researchers analyzed medical records from northern Denmark from 1991 through 2009 and identified 1,974 diagnoses of squamous cell carcinoma, 13,316 diagnoses of basal cell carcinoma, and 3,242 diagnoses of malignant melanoma. They compared information, including prescription data, from these patients with information from 178,655 individuals without skin cancer.
