有些人覺(jué)得年輕時(shí)應(yīng)該多鍛煉身體,，年紀(jì)大了再開始鍛煉可能就沒(méi)什么用了。而學(xué)術(shù)刊物《循環(huán)》（Circulation）發(fā)表的英國(guó)的一項(xiàng)研究顯示,，即便是50歲才開始鍛煉身體，堅(jiān)持鍛煉者的一些健康指標(biāo)也會(huì)好于運(yùn)動(dòng)量不夠的人群。
英國(guó)倫敦大學(xué)學(xué)院等機(jī)構(gòu)的研究人員報(bào)告說(shuō),，他們對(duì)4000多名中老年人進(jìn)行了為期10年的跟蹤調(diào)查,，調(diào)查對(duì)象在研究開始時(shí)平均年齡約49歲。
調(diào)查顯示,，其中約一半人的運(yùn)動(dòng)量達(dá)到推薦標(biāo)準(zhǔn),，即每周超過(guò)2.5小時(shí)從事運(yùn)動(dòng)強(qiáng)度中等或更劇烈的體育鍛煉。這種運(yùn)動(dòng)強(qiáng)度的直觀體現(xiàn)是鍛煉時(shí)心跳加速并可能出汗,，跑步,、打球等許多運(yùn)動(dòng)方式都能達(dá)到這樣的強(qiáng)度。
研究人員分析了受調(diào)查人群的健康指標(biāo),，與不怎么愛(ài)運(yùn)動(dòng)的人相比,，運(yùn)動(dòng)量達(dá)標(biāo)者體內(nèi)的C反應(yīng)蛋白等與發(fā)炎相關(guān)的指標(biāo)性物質(zhì)含量更低。發(fā)炎通常被認(rèn)為與心血管病風(fēng)險(xiǎn)有關(guān),，而心血管病是老年人?；嫉募膊。虼松鲜鼋Y(jié)果也說(shuō)明堅(jiān)持鍛煉的人群身體情況普遍更好,。
參與這項(xiàng)研究的馬克·哈默說(shuō),，以前有關(guān)鍛煉能保護(hù)心臟的研究多是短期的，本次研究持續(xù)10年,，證實(shí)了鍛煉的長(zhǎng)期效果,，并且這種效果在50多歲的年齡較大者身上也能體現(xiàn)出來(lái)。這些人即將退休,，如果能利用退休后的空閑時(shí)間多鍛煉身體,，會(huì)對(duì)健康很有好處,。（生物谷Bioon.com）
doi:10.1161/CIRCULATIONAHA.112.103879
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Physical Activity and Inflammatory Markers Over 10 Years: Follow-Up in Men and Women from the Whitehall II Cohort Study
Mark Hamer1*; Severine Sabia1; G. David Batty1; Martin J. Shipley1; Adam G. Tabàk2; Archana Singh-Manoux3; Mika Kivimaki1
Background—Inflammatory processes are putative mechanisms underlying the cardio-protective effects of physical activity. An inverse association between physical activity and inflammation has been demonstrated but no long-term prospective data are available. We therefore examined the association between physical activity and inflammatory markers over a 10-year follow-up period. Methods and Results—Participants were 4289 men and women (mean age 49.2 years) from the Whitehall II cohort study. Self-reported physical activity and inflammatory markers (serum high-sensitivity C-reactive protein [CRP] and interleukin-6 [IL-6]) were measured at baseline (1991) and follow-up (2002). Forty-nine percent of the participants adhered to standard physical activity recommendations for cardiovascular health (2.5 hours per week moderate to vigorous physical activity) across all assessments. Physically active participants at baseline had lower CRP and IL6 levels and this difference remained stable over time. In comparison to participants that rarely adhered to physical activity guidelines over the 10 years follow-up, the high adherence group displayed lower logeCRP (β=-0.07, 95% CI, -0.12, -0.02) and logeIL-6 (β=-0.07, 95% CI, -0.10, -0.03) at follow up after adjustment for a range of covariates. Compared to participants that remained stable, those that reported an increase in physical activity of at least 2.5 hours/wk displayed lower loge CRP (B coefficient =-0.05, 95% CI, -0.10, -0.001) and loge IL-6 (B coefficient =-0.06, 95% CI, -0.09, -0.03) at follow up. Conclusions—Regular physical activity is associated with lower markers of inflammation over 10 years of follow-up and thus may be important in preventing the pro-inflammatory state seen with ageing.
