德國(guó)研究人員發(fā)現(xiàn)，母親的壓力會(huì)蔓延到她的子宮內(nèi)的嬰兒身上,，可能會(huì)造成持久的影響,。
他們發(fā)現(xiàn)，如果母親高度地處于壓力之下,，嬰兒的應(yīng)激激素出現(xiàn)變化,，如果有家庭暴力，這對(duì)于嬰兒就有影響,。而這種壓力嬰兒自己是無(wú)法控制的,。
壓力會(huì)導(dǎo)致日后的精神疾病和行為問(wèn)題。
一個(gè)針對(duì)25名婦女的小型研究發(fā)現(xiàn),，他們的孩子現(xiàn)在年齡介乎10至19歲,。研究結(jié)果發(fā)表在《轉(zhuǎn)化精神病學(xué)》雜志上。
研究人員指出,，參與這項(xiàng)研究的婦女中,，除非有特殊的家庭情況，大多數(shù)孕婦不會(huì)有這樣大的壓力,。
此外,，研究人員說(shuō)，結(jié)果并不是決定性的,，還有許多其它的因素,，包括兒童成長(zhǎng)可能涉及到的社會(huì)環(huán)境。
但他們懷疑,，在孩子處在子宮中這個(gè)最早的環(huán)境是關(guān)鍵的,。
在他們的研究中，他們調(diào)查了母親和孩子有無(wú)任何不尋常的基因,。
一些十幾歲的孩子就有了一種特殊的基因的變化,，所謂的糖皮質(zhì)激素受體(GR),它可以幫助調(diào)節(jié)人體的激素應(yīng)激反應(yīng)。
這種遺傳變異通常發(fā)生在嬰兒在子宮中的成長(zhǎng)階段,。
科學(xué)家們相信,，正是由于他們的母親精神健康不佳，導(dǎo)致在懷孕期間觸發(fā)了這種基因的變異,。(生物谷 Bioon.com)
生物谷推薦原文出處：
Translational Psychiatry doi:10.1038/tp.2011.21
Transgenerational impact of intimate partner violence on methylation in the promoter of the glucocorticoid receptor
K M Radtke1, M Ruf1, H M Gunter, K Dohrmann, M Schauer, A Meyer and T Elbert
Prenatal exposure to maternal stress can have lifelong implications for psychological function, such as behavioral problems and even the development of mental illness. Previous research suggests that this is due to transgenerational epigenetic programming of genes operating in the hypothalamic–pituitary–adrenal axis, such as the glucocorticoid receptor (GR). However, it is not known whether intrauterine exposure to maternal stress affects the epigenetic state of these genes beyond infancy. Here, we analyze the methylation status of the GR gene in mothers and their children, at 10–19 years after birth. We combine these data with a retrospective evaluation of maternal exposure to intimate partner violence (IPV). Methylation of the mother's GR gene was not affected by IPV. For the first time, we show that methylation status of the GR gene of adolescent children is influenced by their mother's experience of IPV during pregnancy. As these sustained epigenetic modifications are established in utero, we consider this to be a plausible mechanism by which prenatal stress may program adult psychosocial function.
