生物谷 www.bioon.net 針灸銀針可以鎮(zhèn)痛,,為什么,?5月底,,發(fā)表于Nature NeuroScience雜志的研究解釋了其中原因,。
美國(guó)羅徹斯特大學(xué)研究小組稱,針灸過程中,,腺苷在其中扮演了重要作用。研究者通過添加治療白血病藥品的老鼠得出了針灸的正效應(yīng)增大3倍的結(jié)論,。
腺苷是一種天然鎮(zhèn)痛劑,。具有調(diào)節(jié)睡眠、影響心臟和抵抗炎癥等功能,。腺苷在受傷后皮膚中,,可以抑制神經(jīng)來達(dá)到環(huán)節(jié)疼痛的目的,這與利多卡因(lidocaine 生物醫(yī)藥大辭典提供翻譯)的作用方式類似,。
最近,,科學(xué)家發(fā)現(xiàn)針灸產(chǎn)生信號(hào)使得大腦分泌了可鎮(zhèn)痛的腺苷。該研究小組組長(zhǎng)Maiken Nedergaard稱新發(fā)現(xiàn)為針灸增添了科學(xué)依據(jù),。研究通過以小白鼠作為實(shí)驗(yàn)對(duì)象,,通過對(duì)其進(jìn)行針刺激其足三里(位于膝蓋附件穴位),每次針刺激時(shí)間30分鐘,。所選細(xì)針,、針刺時(shí)輕柔輕旋5分鐘。觀察腺苷水平,,結(jié)果表明,,針刺激減少不適程度達(dá)2/3。
美國(guó)國(guó)立衛(wèi)生研究院(NIH)補(bǔ)償與替代醫(yī)學(xué)中心主任Josephine P. Briggs 博士認(rèn)為研究針灸可能激發(fā)多種機(jī)制,腺苷在針灸過程中扮演的新角色,,為理解針灸的意義重大,。(生物谷Bioon.net)
關(guān)于針灸的更多閱讀
Brain Research:針灸可引起大腦神經(jīng)變化
針灸療法找到了科學(xué)依據(jù)
BMJ:針灸可傳播肝炎艾滋病
程莘農(nóng)
生物谷推薦原文出處:
Nature Neuroscience doi:10.1038/nn.2562
Adenosine A1 receptors mediate local anti-nociceptive effects of acupuncture
Nanna Goldman,Michael Chen,Takumi Fujita,Qiwu Xu,Weiguo Peng,Wei Liu,Tina K Jensen,Yong Pei,Fushun Wang,Xiaoning Han,Jiang-Fan Chen,Jurgen Schnermann,Takahiro Takano,Lane Bekar,Kim Tieu& Maiken Nedergaard
Acupuncture is an invasive procedure commonly used to relieve pain. Acupuncture is practiced worldwide, despite difficulties in reconciling its principles with evidence-based medicine. We found that adenosine, a neuromodulator with anti-nociceptive properties, was released during acupuncture in mice and that its anti-nociceptive actions required adenosine A1 receptor expression. Direct injection of an adenosine A1 receptor agonist replicated the analgesic effect of acupuncture. Inhibition of enzymes involved in adenosine degradation potentiated the acupuncture-elicited increase in adenosine, as well as its anti-nociceptive effect. These observations indicate that adenosine mediates the effects of acupuncture and that interfering with adenosine metabolism may prolong the clinical benefit of acupuncture.