美國(guó)波士頓學(xué)院和賓州大學(xué)的科學(xué)家發(fā)現(xiàn)了一種人大腦運(yùn)轉(zhuǎn)及識(shí)別周?chē)h(huán)境的新方式,。相關(guān)研究發(fā)表在近期的《自然—神經(jīng)科學(xué)》雜志上,。
研究人員要求被試者分別看兩組照片:一組是四種場(chǎng)景(廚房、浴室,、道路交叉口和游樂(lè)場(chǎng)),,另一種是上述場(chǎng)景中的個(gè)別物體(冰箱、浴缸,、汽車(chē)和滑坡),;之后對(duì)被試者大腦進(jìn)行功能性磁共振成像掃描。
研究人員發(fā)現(xiàn),,被試者能夠利用由個(gè)別物體產(chǎn)生的大腦模式來(lái)辨認(rèn)由場(chǎng)景產(chǎn)生的大腦模式,,并且能夠及時(shí)說(shuō)出場(chǎng)景的類(lèi)型。
該研究領(lǐng)導(dǎo)者肖恩·麥克沃伊(Sean MacEvoy)表示,,該研究揭示了一個(gè)大腦利用物體信息來(lái)辨別位置的新系統(tǒng),,有助于研發(fā)治療大腦創(chuàng)傷的方法。(生物谷 Bioon.com)
doi:10.1038/nn.2903
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Constructing scenes from objects in human occipitotemporal cortex
Sean P MacEvoy& Russell A Epstein
Many persistent pain states (pain lasting for hours, days, or longer) are poorly treated because of the limitations of existing therapies. Analgesics such as nonsteroidal anti-inflammatory drugs and opioids often provide incomplete pain relief and prolonged use results in the development of severe side effects. Identification of the key mediators of various types of pain could improve such therapies. Here, we tested the hypothesis that hitherto unrecognized cytokines and chemokines might act as mediators in inflammatory pain. We used ultraviolet B (UVB) irradiation to induce persistent, abnormal sensitivity to pain in humans and rats. The expression of more than 90 different inflammatory mediators was measured in treated skin at the peak of UVB-induced hypersensitivity with custom-made