盡管污水處理廠已經(jīng)使用了一些先進(jìn)的技術(shù),,但是仍然發(fā)現(xiàn)城市污水處理廠是一些耐藥基因的重要來源,。
目前,發(fā)表在權(quán)威的Environmental Science & Technology期刊上一項(xiàng)針對(duì)位于美國明尼蘇達(dá)州德盧斯市(Duluth)的蘇必利爾湖的最新的有關(guān)城市污水處理研究的結(jié)果"Tertiary-Treated Municipal Wastewater is a Significant Point Source of Antibiotic Resistance Genes into Duluth-Superior Harbor"揭示了這樣一個(gè)恐怖的結(jié)果,,從城市污水處理廠排放到湖泊和河流中的水可能含有高濃度的生物基因,,而這些生物基因?qū)?huì)導(dǎo)致其產(chǎn)生超強(qiáng)的耐藥性。
據(jù)該項(xiàng)研究的負(fù)責(zé)人Timothy M. LaPara以及他的團(tuán)隊(duì)稱,,抗藥性細(xì)菌在從污水處理廠排放至河流的污水中大量被發(fā)現(xiàn),,這種細(xì)菌是當(dāng)今醫(yī)學(xué)發(fā)展的重大課題。眾所周知,,污水處理的目的就是要試圖殺掉細(xì)菌,,同時(shí),清除掉污水中大量的細(xì)菌基因,,但是科學(xué)家也很驚訝這些經(jīng)過處理后的細(xì)菌基因會(huì)產(chǎn)生出超級(jí)耐藥性,。
研究發(fā)現(xiàn),這些基因,,或者是這些細(xì)菌可能會(huì)被釋放在污水處理廠排出的污水中,。為了能夠確定城市污水處理廠即是抗藥性細(xì)菌基因的重要來源,科學(xué)家們研究了德盧斯城市污水處理廠釋放出的細(xì)菌基因,。盡管德盧斯城市污水處理廠已經(jīng)使用了一些先進(jìn)的技術(shù)來凈化污水,,也就是被稱為廢水的三級(jí)處理方案,但是,,此次的研究仍然發(fā)現(xiàn)城市污水處理廠是這種耐藥基因的重要來源,。
例如,在13個(gè)不同的地點(diǎn)抽樣來的水標(biāo)本中,,科學(xué)家們檢驗(yàn)出了三種基因,,這些基因會(huì)使得其中的細(xì)菌對(duì)四環(huán)素組抗生素產(chǎn)生耐藥性,而這些抗生素常常被用于治療多種疾病,,這些疾病包括痔瘡,,以及一些性傳播疾病,炭疽病和黑死病等,。
LaPara的研究團(tuán)隊(duì)表示,,他們的研究證明即使是那些具有高科技處理水平的污水處理廠也可能是抗藥性細(xì)菌基因的主要來源,所以對(duì)于污水處理廠千萬不能掉以輕心,。(生物谷Bioon.com)
doi:10.1021/es202775r
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Tertiary-Treated Municipal Wastewater is a Significant Point Source of Antibiotic Resistance Genes into Duluth-Superior Harbor
Timothy M. LaPara*†, Tucker R. Burch†, Patrick J. McNamara†, David T. Tan†, Mi Yan‡, and Jessica J. Eichmiller§
In this study, the impact of tertiary-treated municipal wastewater on the quantity of several antibiotic resistance determinants in Duluth-Superior Harbor was investigated by collecting surface water and sediment samples from 13 locations in Duluth-Superior Harbor, the St. Louis River, and Lake Superior. Quantitative PCR (qPCR) was used to target three different genes encoding resistance to tetracycline (tet(A), tet(X), and tet(W)), the gene encoding the integrase of class 1 integrons (intI1), and total bacterial abundance (16S rRNA genes) as well as total and human fecal contamination levels (16S rRNA genes specific to the genus Bacteroides). The quantities of tet(A), tet(X), tet(W), intI1, total Bacteroides, and human-specific Bacteroides were typically 20-fold higher in the tertiary-treated wastewater than in nearby surface water samples. In contrast, the quantities of these genes in the St. Louis River and Lake Superior were typically below detection. Analysis of sequences of tet(W) gene fragments fro...