根據(jù)2011年12月28日在線發(fā)表在《PLoS ONE》期刊上的一篇研究論文,，人皮膚上的微生物決定著人對(duì)蚊子的吸引程度，這可能對(duì)瘧疾傳染和預(yù)防有著重要的影響,。
如果沒有細(xì)菌，人汗液對(duì)于人鼻子而言是無味的,，因此皮膚上的微生物群落在產(chǎn)生每個(gè)人特異性的體味上發(fā)揮著關(guān)鍵性作用,。
荷蘭瓦格寧根大學(xué)(Wageningen University)Niels Verhulst領(lǐng)導(dǎo)的一個(gè)研究小組對(duì)嚴(yán)格上講是岡比亞瘧蚊(Anopheles gambiae)的蚊子開展實(shí)驗(yàn)，而已知這種蚊子在瘧疾傳染上發(fā)揮著重要作用,。
他們發(fā)現(xiàn)如果皮膚上有更加高豐度的但是種類多樣性更加低的細(xì)菌,，那么這個(gè)人對(duì)這種特定的蚊子更加有吸引力。
他們猜測(cè)皮膚上有更加多樣性菌群(microbiota)的個(gè)人可能含有一組選擇性的細(xì)菌,，它們能夠釋放化合物從而干擾正常條件下人宿主對(duì)蚊子的吸引性,，使得這些人更加沒有吸引性，因而感染瘧疾的風(fēng)險(xiǎn)更低,。這些發(fā)現(xiàn)可能導(dǎo)致人們開發(fā)出預(yù)防瘧疾的個(gè)人化方法,。(生物谷：towersimper編譯)
doi:10.1371/journal.pone.0028991
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Composition of Human Skin Microbiota Affects Attractiveness to Malaria Mosquitoes
Niels O. Verhulst, Yu Tong Qiu, Hans Beijleveld, Chris Maliepaard, Dan Knights, Stefan Schulz, Donna Berg-Lyons, Christian L. Lauber, Willem Verduijn, Geert W. Haasnoot, Roland Mumm, Harro J. Bouwmeester, Frans H. J. Claas, Marcel Dicke, Joop J. A. van Loon, Willem Takken, Rob Knight, Renate C. Smallegange
The African malaria mosquito Anopheles gambiae sensu stricto continues to play an important role in malaria transmission, which is aggravated by its high degree of anthropophily, making it among the foremost vectors of this disease. In the current study we set out to unravel the strong association between this mosquito species and human beings, as it is determined by odorant cues derived from the human skin. Microbial communities on the skin play key roles in the production of human body odour. We demonstrate that the composition of the skin microbiota affects the degree of attractiveness of human beings to this mosquito species. Bacterial plate counts and 16S rRNA sequencing revealed that individuals that are highly attractive to An. gambiae s.s. have a significantly higher abundance, but lower diversity of bacteria on their skin than individuals that are poorly attractive. Bacterial genera that are correlated with the relative degree of attractiveness to mosquitoes were identified. The discovery of the connection between skin microbial populations and attractiveness to mosquitoes may lead to the development of new mosquito attractants and personalized methods for protection against vectors of malaria and other infectious diseases.
