如果男性的食指比無名指長,，他們患前列腺癌的風(fēng)險(xiǎn)會(huì)減少三分之一,，其中的年輕男性患前列腺癌的風(fēng)險(xiǎn)更小,。
英國癌癥研究中心的羅斯教授稱：“我們的研究結(jié)果表示,，手指相對(duì)的長度可以用于衡量前列腺癌的風(fēng)險(xiǎn)，尤其是對(duì)于年齡小于60歲的男性,。”
據(jù)她介紹,，除了基因和家庭遺傳因素之外，手指的長度將會(huì)幫助醫(yī)生確定哪些人需要接受常規(guī)的檢查,。
從1994年到2005年,，羅斯和她的同事調(diào)查了1500名前列腺癌患者和 3000名健康男性。
在這些前列腺癌患者中,，大多數(shù)的人的食指比無名指短,。而無名指和食指同樣長的男性,，占總調(diào)查人數(shù)的19%,，患癌風(fēng)險(xiǎn)同樣較大。
而對(duì)于食指較長的人,，他們患前列腺癌的風(fēng)險(xiǎn)則降低33%,。在這些人中，60歲以下的人,，87%都不會(huì)患前列腺癌,。
據(jù)介紹，這兩個(gè)手指的長度,，在人們出生之前就決定了,，它們顯示了不同水平性激素，食指越長的人睪丸素越低,。而據(jù)早期的研究顯示,，睪丸素的多少?zèng)Q定患前列腺癌的風(fēng)險(xiǎn)。
對(duì)于此種相關(guān),，潛在的因素是兩個(gè)基因——HOXA和HOXD,，這兩個(gè)基因不僅控制手指的長度還控制性器官的發(fā)展。（生物谷Bioon.com）
生物谷推薦原文出處：
British Journal of Cancer doi: 10.1038/sj.bjc.6605986
Hand pattern indicates prostate cancer risk
A A Rahman1, A Lophatananon2, S S Brown2, D Harriss3, J Anderson4, T Parker5, D Easton6, Z Kote-Jarai7, R Pocock8, D Dearnaley7, M Guy7, L O'Brien7, R A Wilkinson7, A L Hall9, E Sawyer7, E Page7, J-F Liu10, The UK Genetic Prostate Cancer Study Collaborators11, British Association of Urological Surgeons' Section of Oncology11, R A Eeles7,9,12 and K Muir2,12
1Division of Epidemiology and Public Health, University of Nottingham, Queens Medical Centre, Nottingham NG7 2UH, UK
2Health Sciences Research Institute, Warwick Medical School, Warwick University, Coventry CV4 7AL, UK
3Nottingham Urology Centre, Nottingham University Hospital NHS Trust, Nottingham NG5 1PB, UK
4Royal Hallamshire Hospital, Glossop Road, Sheffield S10 2JF, UK
5School of Biomedical sciences, University of Nottingham, Queens Medical Centre, Nottingham NG7 2UH, UK
6CR-UK Genetic Epidemiology Unit, Strangeways Research Laboratories, Worts Causeway, Cambridge CB1 8RN, UK
7The Institute of Cancer Research, 15 Cotswold Road, Sutton, Surrey SM2 5 NG, UK
8Royal Devon and Exeter NHS Foundation Trust, Barrack Road, Exeter EX2 5DW, UK
9The Royal Marsden NHS Foundation Trust, Downs Road, Sutton SM2 5PT, UK
10Children's Brain Tumour Research, Division of Child Health, University of Nottingham, Queens Medical Centre, Nottingham NG7 2UH, UK
Abstract
Background:
The ratio of digit lengths is fixed in utero, and may be a proxy indicator for prenatal testosterone levels.
Methods:
We analysed the right-hand pattern and prostate cancer risk in 1524 prostate cancer cases and 3044 population-based controls.
Results:
Compared with index finger shorter than ring finger (low 2D?:?4D), men with index finger longer than ring finger (high 2D?:?4D) showed a negative association, suggesting a protective effect with a 33% risk reduction (odds ratio (OR) 0.67, 95% confidence interval (CI) 0.57–0.80). Risk reduction was even greater (87%) in age group <60 (OR 0.13, 95% CI 0.09–0.21).
Conclusion:
Pattern of finger lengths may be a simple marker of prostate cancer risk, with length of 2D greater than 4D suggestive of lower risk.
Keywords:
prostate cancer; hand pattern; case–control study
