近日,,刊登在新一期《英國(guó)癌癥雜志》上瑞典的一項(xiàng)新研究"Red and processed meat consumption and risk of pancreatic cancer: meta-analysis of prospective studies"顯示,,經(jīng)常吃西方食譜中經(jīng)過(guò)加工的肉類(lèi)與胰腺癌患病風(fēng)險(xiǎn)升高之間存在關(guān)聯(lián),。
瑞典卡羅琳醫(yī)學(xué)院在上報(bào)告說(shuō),,與不吃加工肉的人相比,,如果某人每天食用50克加工肉,,例如一根香腸或兩片培根,,那么其患胰腺癌的幾率要高出19%,。與不食用紅肉(包括牛肉、羊肉,、豬肉)的男性相比,,每天吃120克紅肉的男性患胰腺癌的幾率會(huì)高出29%,但此次研究未發(fā)現(xiàn)紅肉對(duì)女性胰腺有何顯著影響,。
這項(xiàng)研究由卡羅琳醫(yī)學(xué)院和瑞典癌癥基金會(huì)共同發(fā)起,,研究人員對(duì)涉及6000名胰腺癌患者的11項(xiàng)研究結(jié)果進(jìn)行分析對(duì)比。負(fù)責(zé)該研究的卡羅琳醫(yī)學(xué)院副教授蘇珊娜·拉爾松說(shuō),,胰腺癌患者的存活率很低,,為幫助患者盡早得以診治,了解該病的誘發(fā)原因很重要,。
該報(bào)告還援引英國(guó)癌癥研究中心信息主管薩拉·霍姆的話說(shuō),,盡管現(xiàn)在還無(wú)法百分之百地確定加工肉是否是罹患胰腺癌的決定性因素,更多的研究結(jié)果正等待進(jìn)一步分析,,但這些新數(shù)據(jù)可以提醒人們注意可能存在的誘因,。(生物谷Bioon.com)
doi:10.1038/bjc.2011.585
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PMID:
Red and processed meat consumption and risk of pancreatic cancer: meta-analysis of prospective studies
S C Larsson1 and A Wolk1
Background:
Whether red and processed meat consumption is a risk factor for pancreatic cancer remains unclear. We conducted a meta-analysis to summarise the evidence from prospective studies of red and processed meat consumption and pancreatic cancer risk.
Methods:
Relevant studies were identified by searching PubMed and EMBASE databases through November 2011. Study-specific results were pooled using a random-effects model.
Results:
Eleven prospective studies, with 6643 pancreatic cancer cases, were included in the meta-analysis. An increase in red meat consumption of 120?g per day was associated with an overall relative risk (RR) of 1.13 (95% confidence interval (CI)=0.93–1.39; Pheterogeneity<0.001). Red meat consumption was positively associated with pancreatic cancer risk in men (RR=1.29; 95% CI=1.08–1.53; Pheterogeneity=0.28; five studies), but not in women (RR=0.93; 95% CI=0.74–1.16; Pheterogeneity=0.21; six studies). The RR of pancreatic cancer for a 50?g per day increase in processed meat consumption was 1.19 (95% CI=1.04–1.36; Pheterogeneity=0.46).
Conclusion:
Findings from this meta-analysis indicate that processed meat consumption is positively associated with pancreatic cancer risk. Red meat consumption was associated with an increased risk of pancreatic cancer in men. Further prospective studies are needed to confirm these findings.