科學(xué)家們?cè)?月出版的《自然—生物技術(shù)》期刊上報(bào)告說(shuō),，他們測(cè)出一種植物寄生型線蟲(chóng)的基因組序列,，這是首次測(cè)出已知植物寄生型多細(xì)胞動(dòng)物的基因組序列，從而讓大家能夠瞥見(jiàn)無(wú)性動(dòng)物的原始生命之光,，這類根結(jié)線蟲(chóng)的雄性對(duì)后代的衍生沒(méi)有貢獻(xiàn),。
據(jù)估計(jì)，寄生性蛔蟲(chóng)每年對(duì)全球谷物所造成的損失經(jīng)費(fèi)高達(dá)1570億美元,，控制它們的化學(xué)物質(zhì)又會(huì)對(duì)人體和環(huán)境造成危害,。
歐美27個(gè)實(shí)驗(yàn)室的54位科學(xué)家組織團(tuán)隊(duì)，對(duì)南方根結(jié)線蟲(chóng)的基因組進(jìn)行測(cè)序和分析,。南方根結(jié)線蟲(chóng)的破壞性極大,，會(huì)在許多重要作物如西紅柿、棉花,、咖啡的樹(shù)根部繁殖,。
線蟲(chóng)是一種非寄生型線蟲(chóng)，發(fā)育生物學(xué)家們對(duì)這種非寄生型線蟲(chóng)進(jìn)行了深入的研究,。借助于對(duì)這種線蟲(chóng)的研究知識(shí),，歐美研究團(tuán)隊(duì)發(fā)現(xiàn)了南方根結(jié)線蟲(chóng)借樹(shù)根養(yǎng)活自己。線蟲(chóng)和南方根結(jié)線蟲(chóng)有相同的基因,，也許,，它們將成為研制對(duì)環(huán)境更友好的殺蟲(chóng)劑的極好靶標(biāo)。（生物谷Bioon.com）
生物谷推薦原始出處：
Nature Biotechnology,，doi: 10.1038/nbt.1482,，Pierre Abad，Patrick Wincker
Genome sequence of the metazoan plant-parasitic nematode Meloidogyne incognita
Pierre Abad1,2,3, Jér?me Gouzy4, Jean-Marc Aury5,6,7, Philippe Castagnone-Sereno1,2,3, Etienne G J Danchin1,2,3, Emeline Deleury1,2,3, Laetitia Perfus-Barbeoch1,2,3, Véronique Anthouard5,6,7, Fran?ois Artiguenave5,6,7, Vivian C Blok8, Marie-Cécile Caillaud1,2,3, Pedro M Coutinho9, Corinne Dasilva5,6,7, Francesca De Luca10, Florence Deau1,2,3, Magali Esquibet11, Timothé Flutre12, Jared V Goldstone13, Noureddine Hamamouch14, Tarek Hewezi15, Olivier Jaillon5,6,7, Claire Jubin5,6,7, Paola Leonetti10, Marc Magliano1,2,3, Tom R Maier15, Gabriel V Markov16,17, Paul McVeigh18, Graziano Pesole19,20, Julie Poulain5,6,7, Marc Robinson-Rechavi21,22, Erika Sallet23,24, Béatrice Ségurens5,6,7, Delphine Steinbach12, Tom Tytgat25, Edgardo Ugarte5,6,7, Cyril van Ghelder1,2,3, Pasqua Veronico10, Thomas J Baum15, Mark Blaxter26, Teresa Bleve-Zacheo10, Eric L Davis14, Jonathan J Ewbank27, Bruno Favery1,2,3, Eric Grenier11, Bernard Henrissat9, John T Jones8, Vincent Laudet16, Aaron G Maule18, Hadi Quesneville12, Marie-No?lle Rosso1,2,3, Thomas Schiex24, Geert Smant25, Jean Weissenbach5,6,7 & Patrick Wincker5,6,7
Plant-parasitic nematodes are major agricultural pests worldwide and novel approaches to control them are sorely needed. We report the draft genome sequence of the root-knot nematode Meloidogyne incognita, a biotrophic parasite of many crops, including tomato, cotton and coffee. Most of the assembled sequence of this asexually reproducing nematode, totaling 86 Mb, exists in pairs of homologous but divergent segments. This suggests that ancient allelic regions in M. incognita are evolving toward effective haploidy, permitting new mechanisms of adaptation. The number and diversity of plant cell wall–degrading enzymes in M. incognita is unprecedented in any animal for which a genome sequence is available, and may derive from multiple horizontal gene transfers from bacterial sources. Our results provide insights into the adaptations required by metazoans to successfully parasitize immunocompetent plants, and open the way for discovering new antiparasitic strategies.
INRA, UMR 1301, 400 route des Chappes, F-06903 Sophia-Antipolis, France.
CNRS, UMR 6243, 400 route des Chappes, F-06903 Sophia-Antipolis, France.
UNSA, UMR 1301, 400 route des Chappes, F-06903 Sophia-Antipolis, France.
Laboratoire Interactions Plantes Micro-organismes, UMR441/2594, INRA/CNRS, Chemin de Borde Rouge, BP 52627, F-31320 Castanet Tolosan, France.
Genoscope (CEA), 2 rue Gaston Crémieux, CP5706, F-91057 Evry, France.
CNRS, UMR 8030, 2 rue Gaston Crémieux, CP5706, F-91057 Evry, France.
Université d'Evry, F-91057 Evry, France.
Plant Pathology Programme, SCRI, Invergowrie, Dundee DD2 5DA, UK.
CNRS, UMR 6098 CNRS and Universités d'Aix-Marseille I & II, Case 932, 163 Av. de Luminy, F-13288 Marseille, France.
Istituto per la Protezione delle Piante, Consiglio Nazionale delle Ricerche, Via G. Amendola 165/a, 70126 Bari, Italy.
INRA, Agrocampus Rennes, Univ. Rennes I, UMR1099 BiO3P, Domaine de la Motte, F-35653 Le Rheu Cedex, France.
INRA, UR1164 Unité de Recherche en Génomique et Informatique (URGI), 523 place des terrasses de l'Agora, F-91034 Evry, France.
Biology Department, Woods Hole Oceanographic Institution, Co-op Building, MS #16, Woods Hole, Massachusetts 02543, USA.
Department of Plant Pathology, North Carolina State University, 840 Method Road, Unit 4, Box 7903 Raleigh, North Carolina 27607, USA.
Department of Plant Pathology, Iowa State University, 351 Bessey Hall, Ames, Iowa 50011, USA.
Université de Lyon, Institut de Génomique Fonctionnelle de Lyon, Molecular Zoology team, Ecole Normale Supérieure de Lyon, Université Lyon 1, CNRS, INRA, Institut Fédératif 128 Biosciences Gerland, Lyon Sud, 46 allée d'Italie, F-69364 Lyon Cedex 07, France.
USM 501, Evolution des Régulations Endocriniennes, Muséum National d'Histoire Naturelle, 7 rue Cuvier, F-75005 Paris, France.
Biomolecular Processes: Parasitology, School of Biological Sciences, Medical Biology Centre, 97 Lisburn Road, Queen's University Belfast, Belfast BT9 7BL, UK.
Dipartimento di Biochimica e Biologia Molecolare "E. Quagliariello", University of Bari, Via Orabona 4, 70126 Bari, Italy.
Istituto Tecnologie Biomediche, Consiglio Nazionale delle Ricerche, Via G. Amendola, 122/D, 70126 Bari, Italy.
Department of Ecology and Evolution, University of Lausanne, UNIL-Sorge, Le Biophore, CH-1015 Lausanne, Switzerland.
Swiss Institute of Bioinformatics, quartier sorge, Batiment Genopode, CH-1015 Lausanne, Switzerland.
Plateforme Bioinformatique du Génopole Toulouse Midi-Pyrénées, GIS Toulouse Genopole, 24 Chemin de Borde Rouge, BP 52627, F-31320 Castanet Tolosan, France.
Unité de Biométrie et d'Intelligence Artificielle UR875, INRA, Chemin de Borde Rouge, BP 52627, F-31320 Castanet Tolosan, France.
Laboratory of Nematology, Wageningen University, Binnenhaven 5, 6709PD Wageningen, The Netherlands.
Institute of Evolutionary Biology, University of Edinburgh, Kings Buildings, Ashworth Laboratories, West Mains Road, Edinburgh EH9 3JT, UK.
INSERM/CNRS/Université de la Méditerranée, Centre d'Immunologie de Marseille-Luminy, 163 av. de Luminy, Case 906, F-13288, Marseille cedex 09, France.
