野生中華鱘（Acipenser sinensis）種群數(shù)量急劇下降可能是一種滲透到這種鱘的棲息地的涂料化學(xué)物質(zhì)造成的。
Jianying Hu及其同事證明了一種名為T(mén)PT的含錫有機(jī)物可以進(jìn)入鱘的卵,，而且造成了眼畸形和骨骼缺損,。這組科學(xué)家發(fā)現(xiàn)，雌性鱘可以把TPT轉(zhuǎn)移到它們的卵中，其濃度對(duì)在長(zhǎng)江受精或孵化的幼魚(yú)造成了顯著的風(fēng)險(xiǎn)。這組作者發(fā)現(xiàn)，從長(zhǎng)江中捕獲的7.5%的中華鱘幼魚(yú)有眼或骨骼畸形,。在實(shí)驗(yàn)中讓中華鱘和西伯利亞鱘（A. baerii）接觸較高TPT濃度導(dǎo)致了畸形發(fā)生的增加，畸形發(fā)生率符合在接觸類(lèi)似濃度的該化合物的野生種群中見(jiàn)到的發(fā)生率。然而,，接觸了類(lèi)似于在中華鱘卵中發(fā)現(xiàn)的含錫有機(jī)物的西伯利亞鱘卵并沒(méi)有導(dǎo)致顯著數(shù)量的畸形,。這組作者提出，TPT很可能是見(jiàn)于中華鱘的畸形的原因,，而且可能影響了這一物種的迅速衰退,。（生物谷Bioon.com）
生物谷推薦原始出處：
PNAS May 26, 2009, doi: 10.1073/pnas.0809434106
Malformations of the endangered Chinese sturgeon, Acipenser sinensis, and its causal agent
Jianying Hua,1, Zhaobin Zhanga, Qiwei Weib, Huajun Zhena, Yanbin Zhaoa, Hui Penga, Yi Wana, John P. Giesyc,d,e, Luoxin Lib and Bo Zhangf
The anadromous Chinese sturgeon (Acipenser sinensis) is endangered and listed among the first class of protected animals in China. The possible causes for the decline of this species are the effects of synthetic chemicals, and loss of critical habitat. Chinese sturgeon in the Yangtze River have accumulated triphenyltin (TPT) to 31–128 ng/g wet weigh (ww) in liver, which is greater than the concentrations of tributyltin (<1.0 ng/g ww). Maternal transfer of TPT has resulted in concentrations of 25.5 ± 13.0 ng/g ww in eggs of wild Chinese sturgeon, which poses a significant risk to the larvae naturally fertilized or hatched in the Yangtze River. The incidence of deformities in fry was 7.5%, with 1.2% of individuals exhibiting ocular abnormal development, and 6.3% exhibited skeletal/morphological deformations. The incidences of both ocular and skeletal/morphological deformations were directly proportional to the TPT concentration in the eggs of both the Chinese sturgeon and the Siberian sturgeon (Acipenser baerii) in controlled laboratory studies. The rates of deformities in the controlled studies were consistent with the rates caused at the similar concentrations in eggs collected from the field. Thus, TPT is the causal agent to induce the malformation of larvae of Chinese sturgeon. The incidence of deformed larvae of Chinese sturgeon is an indicator of overall population-level effects of TPT on Chinese sturgeon, because TPT at environmentally relevant concentrations can result in significantly decrease both quality and quantity of eggs and spawning frequency of fish.
