一項(xiàng)研究顯示,，不受廣泛使用的驅(qū)蟲劑避蚊胺影響的蚊子可能把這種性狀傳給它們的后代。Linda Field及其同事報(bào)告了一種可能的生物機(jī)制,，它可能解釋為什么一小部分蚊子不怕避蚊胺,，并證明了這種性狀可能是可遺傳的。這組科學(xué)家通過觀察被避蚊胺處理過的人類手臂所吸引的蚊子,，從而發(fā)現(xiàn)了樣本組中對(duì)避蚊胺不敏感的雌蚊,。這組作者發(fā)現(xiàn)，當(dāng)這些雌蚊與對(duì)避蚊胺敏感性未知的雄蚊繁殖后代的時(shí)候,，對(duì)避蚊胺不敏感的蚊子的比例在一代中從13%上升到了超過50%,。
為了尋找對(duì)避蚊胺具有特異性的感覺機(jī)制，這組科學(xué)家使用了一種測量蚊子觸角上特定氣味受體反應(yīng)的技術(shù),。這組作者在埃及伊蚊的觸角上發(fā)現(xiàn)了一種感覺神經(jīng)元,，它以取決于劑量的方式對(duì)避蚊胺做出反應(yīng)，而且它的功能可能決定了蚊子個(gè)體對(duì)避蚊胺的敏感程度,。這組作者說,，這項(xiàng)發(fā)現(xiàn)可能用于研究適應(yīng)了其他用于害蟲控制的化學(xué)驅(qū)蟲劑的昆蟲。（生物谷Bioon.com）
生物谷推薦原文出處：
Behavioral insensitivity to DEET in Aedes aegypti is a genetically determined trait residing in changes in sensillum function
Nina M. Stanczyka,b, John F. Y. Brookfieldb, Rickard Ignellc, James G. Logana,1, and Linda M. Fielda
aCentre for Sustainable Pest and Disease Management, Biological Chemistry Department, Rothamsted Research, Harpenden, Hertfordshire, AL5 2JQ, United Kingdom;
bSchool of Biology, University of Nottingham, University Park, Nottingham NG7 2RD, United Kingdom; and
cDivision of Chemical Ecology, Department of Plant Protection Biology, Swedish University of Agricultural Sciences, Box 102,230 53 Alnarp, Sweden
N,N-Diethyl-m-toluamide (DEET) is one of the most effective and commonly used mosquito repellents. However, during laboratory trials a small proportion of mosquitoes are still attracted by human odors despite the presence of DEET. In this study behavioral assays identified Aedes aegypti females that were insensitive to DEET, and the selection of either sensitive or insensitive groups of females with males of unknown sensitivity over several generations resulted in two populations with different proportions of insensitive females. Crossing experiments showed the “insensitivity” trait to be dominant. Electroantennography showed a reduced response to DEET in the selected insensitive line compared with the selected sensitive line, and single sensillum recordings identified DEET-sensitive sensilla that were nonresponders in the insensitive line. This study suggests that behavioral insensitivity to DEET in A. aegypti is a genetically determined dominant trait and resides in changes in sensillum function.
