?7月13日,,費(fèi)城(UPI)—A U.S.科學(xué)家在實(shí)驗(yàn)室里成功完成了動(dòng)物損傷脊髓神經(jīng)束的再生及其肢體活動(dòng)的恢復(fù),。
??Drexel大學(xué)醫(yī)學(xué)院神經(jīng)生物學(xué)與解剖學(xué)專家John Houle的實(shí)驗(yàn)演示了神經(jīng)是如何從動(dòng)物腿部移取并移植到損傷的脊髓束的——由于聯(lián)合了酶的吸收瘢痕組織作用——從而再生,。
??“這項(xiàng)研究對(duì)于如何使脊髓神經(jīng)損傷病人重新恢復(fù)到可以活動(dòng)的狀態(tài)是一個(gè)重要的里程碑”,,Houle說,,“然而仍有大量的工作要做,,以運(yùn)用到患者身上,。”
??他聲稱該研究一個(gè)重要的意義是實(shí)驗(yàn)過程既適用于新受傷的動(dòng)物,,也適用于損傷時(shí)間較長(zhǎng)的動(dòng)物。
??該研究的第二個(gè)重要方面是特殊酶——軟骨素酶的修復(fù)瘢痕組織,、減少其正常抑制狀態(tài)及促進(jìn)邊緣生長(zhǎng)的作用,。
??該研究詳細(xì)內(nèi)容見于《神經(jīng)科學(xué)》雜志。
英文原文:
Study shows spinal cord regeneration
PHILADELPHIA, July 13 (UPI) -- A U.S. scientist has demonstrated in a lab animal the successful regeneration of injured spinal nerve endings and recovery of arm movements.
John Houle, professor of neurobiology and anatomy at Drexel University College of Medicine, demonstrated how a nerve removed from the animal's leg and transplanted across a spinal cord injury -- in combination with enzyme digestion of scar material -- led to regeneration.
"This study represents a major milestone in the battle to return spinal cord injury patients to a state of mobility," said Houle. "However there is still a lot of work to be done to adapt this procedure to human use."
He said a significant aspect of the study is the process applies to animals that are newly injured, as well as in animals with long-term injuries.
A second facet of the study is the ability of the specific enzyme, chondroitinase, to modify scar tissue, reducing its normal inhibitory nature and facilitating growth beyond the bridge.
The research project is detailed in the Journal of Neuroscience.
相關(guān)報(bào)道:
線照射對(duì)受損脊髓軸索和髓鞘的作用