色視覺在視網(wǎng)膜中形成,，在靈長(zhǎng)類動(dòng)物中,，視覺處理的第一階段由視錐細(xì)胞和神經(jīng)節(jié)細(xì)胞的重疊格組成，其中每個(gè)對(duì)視覺空間統(tǒng)一取樣,。
彩色感覺（色覺）由對(duì)來自不同視錐細(xì)胞類型的信號(hào)所做比較,，但這些輸入信號(hào)是怎樣被神經(jīng)節(jié)細(xì)胞（它們傳輸視網(wǎng)膜的輸出）結(jié)合在一起的多年來一直是一個(gè)有爭(zhēng)議的問題。現(xiàn)在,，利用大尺度多電極陣列和細(xì)顆粒視覺模擬,，F(xiàn)ield等人繪制出了單個(gè)視錐細(xì)胞輸入相對(duì)于整個(gè)神經(jīng)節(jié)細(xì)胞群的位置和類型圖，從而以前所未有的分辨率和尺度獲得輸入-輸出對(duì)應(yīng)圖,。（生物谷Bioon.com）
生物谷推薦英文摘要：
Nature doi:10.1038/nature09424
Functional connectivity in the retina at the resolution of photoreceptors
Greg D. Field,Jeffrey L. Gauthier,Alexander Sher,Martin Greschner,Timothy A. Machado,Lauren H. Jepson,Jonathon Shlens,Deborah E. Gunning,Keith Mathieson,Wladyslaw Dabrowski,Liam Paninski,Alan M. Litke& E. J. Chichilnisky
To understand a neural circuit requires knowledge of its connectivity. Here we report measurements of functional connectivity between the input and ouput layers of the macaque retina at single-cell resolution and the implications of these for colour vision. Multi-electrode technology was used to record simultaneously from complete populations of the retinal ganglion cell types (midget, parasol and small bistratified) that transmit high-resolution visual signals to the brain. Fine-grained visual stimulation was used to identify the location, type and strength of the functional input of each cone photoreceptor to each ganglion cell. The populations of ON and OFF midget and parasol cells each sampled the complete population of long- and middle-wavelength-sensitive cones. However, only OFF midget cells frequently received strong input from short-wavelength-sensitive cones. ON and OFF midget cells showed a small non-random tendency to selectively sample from either long- or middle-wavelength-sensitive cones to a degree not explained by clumping in the cone mosaic. These measurements reveal computations in a neural circuit at the elementary resolution of individual neurons.
