英國最新一期Nature雜志的一份報告指出,人腦中控制性活動的神經(jīng)與控制暴力的神經(jīng)很有可能是連結(jié)在一起的,。
美國紐約大學(xué)的神經(jīng)系統(tǒng)專家在小白鼠 身上進(jìn)行了相關(guān)試驗,,他們改變了老鼠腦中控制暴力的神經(jīng)元基因,讓這組神經(jīng)在受到刺激之后亮起藍(lán)光,。
隨后,,專家們對轉(zhuǎn)基因小白鼠進(jìn)行長期觀測,看看在打架和交配時,,究竟是哪些神經(jīng)元在支配它們的大腦,。
許多神經(jīng)元都在小白鼠交配或戰(zhàn)斗時分別被“點亮”,但還存在相當(dāng)數(shù)量的神經(jīng)元,,在這兩種狀態(tài)下都會亮起來———盡管性和暴力一般都站在愛與恨的天平兩端,。
紐約大學(xué)的專家解釋說,小白鼠之所以有同時控制性和暴力的神經(jīng)元,,是為了對異性的侵入者做出適當(dāng)反應(yīng),,即在性興奮 的情況下也能采用暴力手段御敵,不被“糖衣炮彈”擊倒,。專家同時認(rèn)為,,人類腦部也擁有與之類似的神經(jīng)結(jié)構(gòu)。(生物谷Bioon.com)
生物谷推薦原文出處:
Nature doi:10.1038/nature09736
Functional identification of an aggression locus in the mouse hypothalamus
Dayu Lin1, 2 Maureen P. Boyle3 Piotr Dollar4 Hyosang Lee1 E. S. Lein3 Pietro Perona4 David J. Anderson1, 2
Electrical stimulation of certain hypothalamic regions in cats and rodents can elicit attack behaviour, but the exact location of relevant cells within these regions, their requirement for naturally occurring aggression and their relationship to mating circuits have not been clear. Genetic methods for neural circuit manipulation in mice provide a potentially powerful approach to this problem, but brain-stimulation-evoked aggression has never been demonstrated in this species. Here we show that optogenetic, but not electrical, stimulation of neurons in the ventromedial hypothalamus, ventrolateral subdivision (VMHvl) causes male mice to attack both females and inanimate objects, as well as males. Pharmacogenetic silencing of VMHvl reversibly inhibits inter-male aggression. Immediate early gene analysis and single unit recordings from VMHvl during social interactions reveal overlapping but distinct neuronal subpopulations involved in fighting and mating. Neurons activated during attack are inhibited during mating, suggesting a potential neural substrate for competition between these opponent social behaviours.