中國科學(xué)院昆明動物研究所馬原野課題組和胡新天課題組承擔(dān)的國家基金重點項目《獼猴前額葉-頂葉在不同空間坐標(biāo)系處理信息的作用》經(jīng)過五年(2004-2009)的研究,取得較大的進(jìn)展,,該研究團(tuán)隊發(fā)現(xiàn)了靈長類大腦前額葉背側(cè)部涉及到了和“自我”相關(guān)的信息處理。這可能是人類自我意識產(chǎn)生的神經(jīng)基礎(chǔ),。
大腦前額葉是位于靈長類動物和人大腦半球額部的一塊皮層,這塊皮層和靈長類高度發(fā)達(dá)的智力有明顯的關(guān)系,被稱為“腦中之腦”,。盡管對前額葉在腦高級功能中的作用誰都不會懷疑,,但很多具體的細(xì)節(jié)還是不甚清楚,比如背側(cè)大腦前額葉在處理工作記憶信息時,,是否處理所有的空間工作記憶信息?他們的研究結(jié)果清楚地顯示了背側(cè)前額葉僅對自我為中心的空間信息處理負(fù)責(zé),,而與大環(huán)境為中心的空間信息處理無關(guān),。那么其意義是什么呢?在動物界數(shù)千種動物中,,只有人,,大猿,海豚,,大象和鴿子少數(shù)幾種動物能認(rèn)識自己的鏡像,,這種能力被認(rèn)為是自我意識產(chǎn)生的萌芽。在前額葉背側(cè)部,,一些神經(jīng)元可能同動物的體態(tài)語言和”精神圖象”有關(guān),,而語言和精神圖象在自我意識的產(chǎn)生中,有著十分重要的作用,。他們認(rèn)為背側(cè)部前額葉以自我為中心的空間功能可能不僅僅同工作記憶有關(guān),,而更可能同“自我意識” 的產(chǎn)生有著相當(dāng)密切的關(guān)系。
該研究結(jié)果得到了國際相關(guān)研究領(lǐng)域的重視,,最近,,英國一家著名的神經(jīng)科學(xué)雜志Neuroscience & Biobehavioral Reviews(IF 7.8)特邀請該研究團(tuán)隊對其系列研究工作撰寫了一篇綜述文章《The egocentric spatial reference frame used in dorsal–lateral prefrontal working memory in primates, YuanYe Ma et al, 2011 》,。這篇論文現(xiàn)已經(jīng)在網(wǎng)上發(fā)表,。(生物谷Bioon.com)
生物谷推薦原文出處:
Neurosci Biobehav Rev. 2011 Apr 3.
The egocentric spatial reference frame used in dorsal-lateral prefrontal working memory in primates.
Ma Y, Hu X, Wilson FA.
SourceState Key Laboratory of Brain and Cognition, Kunming Institute of Zoology, Chinese Academy of Sciences, 32 Jaochang donglu, Kunming, PR China, 650223; State Key Laboratory of Brain and Cognition, Biophysics, Chinese Academy of Sciences, Beijing, PR China, 100101.
Abstract
The dorsal-lateral prefrontal cortex (dlPFC) has been proposed to be the site of spatial working memory (WM), and this concept has had a profound influence on functional studies of the prefrontal cortex (PFC). The concept of spatial WM has been understood to mean that the location of an object is memorized for a short period of time. However, this concept of space is a simplification. To process the spatial information, different spatial frames can be used. In this review, the authors present data from their own laboratory to argue that the dlPFC is related to the egocentric spatial information processing (ESIP) in WM. The goal of this review is to introduce and discuss the egocentric spatial reference frame (ESRF) located in the dlPFC. The ESIP in the PFC might be involved in self-recognition.