喬治亞大學的研究人員抽樣了14000多只,，于不同條件下飼養(yǎng)的雞只后發(fā)現(xiàn)，即使抑制了家禽飼養(yǎng)場的抗生素使用,，對于減少威脅人類健康之抗藥性細菌的效果仍然不大,。
這四種不同的養(yǎng)殖條件包括給予抗生素的商用雞只、未給與抗生素的商用雞只,、給予抗生素的實驗室養(yǎng)殖用雞只及未給予抗生素的實驗室用雞只,。
喬治亞大學獸醫(yī)學院的教授Margie Lee發(fā)現(xiàn)，養(yǎng)殖于無抗生素農(nóng)場甚至是實驗室中的雞，也含有大量的抗藥性細菌,?？顾幮约毦灰欢▉碜允褂每股氐募仪荩胰【喛股氐氖褂檬聦嵣鲜菦]有幫助的,。
這項研究結(jié)果刊載于3月號的Applied and Environmental Microbiology中,，研究作者建議家禽來到農(nóng)場時體內(nèi)就帶有抗藥性細菌了，這可能從牠們發(fā)育的蛋里就攜帶著這些細菌,。因此必需從引進的家禽來源就開始控管,，而不只是管理養(yǎng)雞場的飼養(yǎng)條件就可以抑制抗藥性細菌的生成。此外,，消費者也應重視烹調(diào)的方式,，必需食用煮熟的肉，而且接觸到生的雞肉后,，一定要洗手后再接觸其它食物,。
(資料來源 : Bio.com)
部分英文原文：
Applied and Environmental Microbiology, March 2007, p. 1404-1414, Vol. 73, No. 5
0099-2240/07/$08.00+0 doi:10.1128/AEM.01193-06
Copyright © 2007, American Society for Microbiology. All Rights Reserved.
Impact of Antimicrobial Usage on Antimicrobial Resistance in Commensal Escherichia coli Strains Colonizing Broiler Chickens
J. L. Smith,1 D. J. V. Drum,1 Y. Dai,1 J. M. Kim,1 S. Sanchez,2 J. J. Maurer,1,3 C. L. Hofacre,1,3 and M. D. Lee1,3*
Poultry Diagnostic and Research Center,1 Athens Diagnostic Laboratory, College of Veterinary Medicine, University of Georgia, Athens, Georgia 30602,2 Center for Food Safety, College of Agriculture and Environmental Sciences, University of Georgia, Griffin, Georgia 302233
Received 23 May 2006/ Accepted 19 December 2006
Escherichia coli strains isolated from commercial broilers and an experimental flock of chickens were screened to determine phenotypic expression of antimicrobial resistance and carriage of drug resistance determinants. The goal of this study was to investigate the influence of oxytetracycline, sarafloxacin, and enrofloxacin administration on the distribution of resistance determinants and strain types among intestinal commensal E. coli strains isolated from broiler chickens. We detected a high prevalence of resistance to drugs such as tetracycline (36 to 97%), sulfonamides (50 to 100%), and streptomycin (53 to 100%) in E. coli isolates from treated and untreated flocks. These isolates also had a high prevalence of class 1 integron carriage, and most of them possessed the streptomycin resistance cassette, aadA1. In order to investigate the contribution of E. coli strain distribution to the prevalence of antimicrobial resistance and the resistance determinants, isolates from each flock were DNA fingerprinted by enterobacterial repetitive intergenic consensus sequence (ERIC) PCR. Although very diverse E. coli strain types were detected, four ERIC strain types were present on all of the commercial broiler farms, and two of the strains were also found in the experimental flocks. Each E. coli strain consisted of both susceptible and antimicrobial agent-resistant isolates. In some instances, isolates of the same E. coli strain expressed the same drug resistance patterns although they harbored different tet determinants or streptomycin resistance genes. Therefore, drug resistance patterns could not be explained solely by strain prevalence, indicating that mobile elements contributed significantly to the prevalence of resistance.
