近日刊登在國際雜志Infection Control and Hospital Epidemiology上的一項(xiàng)研究報(bào)告指出,，紐約市因?yàn)樯鐓^(qū)獲得性耐甲氧西林金黃色葡萄球菌（CA-MRSA）感染所致的住院率超出1997年至2006年的三倍還多,。大多數(shù)的MRSA感染都是在醫(yī)院內(nèi)、醫(yī)療保健過程中獲得感染的,，近年來公共健康專家越來越關(guān)注社區(qū)型如家庭,、學(xué)校等地方的MRSA感染。
3579人已經(jīng)加入了紐約市醫(yī)院關(guān)于CA-MRSA的感染研究中,，CA-MRSA感染率從1997年的113人到2006年的875人,。醫(yī)院收容治療的20%的感染者均為社區(qū)獲得型感染。
研究者的研究發(fā)現(xiàn)揭示了從1997年以來社區(qū)獲得性MRSA感染率的上升,。相比住院治療的病人來說,，研究者指出，相比一般人群,，肥胖者或者感染HIV以及無家可歸的人群更容易感染CA-MRSA,。作者推測了增加的感染風(fēng)險(xiǎn)和人口統(tǒng)計(jì)數(shù)據(jù)、并存病有密切關(guān)系,；在肥胖病人和HIV感染者中常常存在皮膚創(chuàng)傷,，這就為MRSA感染提供了條件。而且男性和孩子由于經(jīng)常進(jìn)行戶外運(yùn)動,，因此感染MRSA的風(fēng)險(xiǎn)也大大增加,。這項(xiàng)研究建議,，應(yīng)該通過抑制社區(qū)獲得性MRSA的感染從而來降低感染風(fēng)險(xiǎn)，增加公眾的健康效應(yīng),。衛(wèi)生部應(yīng)當(dāng)教育那些感染CA-MRSA的無家可歸者,，并且及時(shí)教育人們尋找醫(yī)療求助以及防止疾病互相傳染等等。（生物谷Bioon.com）
編譯自：Community-Acquired MRSA Cases On the Rise in New York City, Study Suggests
編譯者：T.Shen
PMC:
PMID:
Trends in Hospitalization for Community-Associated Methicillin-Resistant Staphylococcus aureus in New York City, 1997-2006: Data from New York State's Statewide Planning and Research Cooperative System.
Farr AM, Aden B, Weiss D, Nash D, Marx MA.
Objective. To describe trends in hospitalizations with community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) infection in New York City over 10 years and to explore the demographics and comorbidities of patients hospitalized with CA-MRSA infections. Design. Retrospective analysis of hospital discharges from New York State's Statewide Planning and Research Cooperative System database from 1997 to 2006. Patients. All patients greater than 1 year of age admitted to New York hospitals with diagnosis codes indicating MRSA who met the criteria for CA-MRSA on the basis of admission information and comorbidities. Methods. We determined hospitalization rates and compared demographics and comorbidities of patients hospitalized with CA-MRSA versus those hospitalized with all other non-MRSA diagnoses by multivariable logistic regression. Results. Of 18,226 hospitalizations with an MRSA diagnosis over 10 years, 3,579 (20%) were classified as community-associated. The CA-MRSA hospitalization rate increased from 1.47 to 10.65 per 100,000 people overall from 1997 to 2006. Relative to non-MRSA hospitalizations, men, children, Bronx and Manhattan residents, the homeless, patients with human immunodeficiency virus (HIV) infection, and persons with diabetes had higher adjusted odds of CA-MRSA hospitalization. Conclusions. The CA-MRSA hospitalization rate appeared to increase between 1997 and 2006 in New York City, with residents of the Bronx and Manhattan, men, and persons with HIV infection or diabetes at increased odds of hospitalization with CA-MRSA. Further studies are needed to explore how changes in MRSA incidence, access to care, and other factors may have impacted these rates.
