8月22日,,“針灸橫切聲波作用新發(fā)現(xiàn)”新聞發(fā)布會(huì)在香港舉行,。由香港大學(xué)、北京大學(xué)等學(xué)校組成的研究團(tuán)隊(duì)經(jīng)過(guò)八年研究發(fā)現(xiàn),,利用磁共振攝影技術(shù),,實(shí)際觀察到針灸震動(dòng)所產(chǎn)生的橫切聲波啟動(dòng)了細(xì)胞內(nèi)鈣離子流及鈣震蕩,從而達(dá)到減輕患者痛苦和治療的作用,。這一研究成果刊登在最新一期《歐洲生理學(xué)學(xué)報(bào)》期刊上,。(生物谷 Bioon.com)
doi:10.1038/nchem.1114
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Signaling and Cell PhysiologyPhysiology and cell biology of acupuncture observed in calcium signaling activated by acoustic shear wave
Geng Li, Jie-Ming Liang, Pei-Wen Li, Xiaoqiang Yao, Peter Zhong Pei, Wei Li, Qi-Hua He, Xifei Yang, Queenie C. C. Chan and Paul Y. S. Cheung, et al
This article presents a novel model of acupuncture physiology based on cellular calcium activation by an acoustic shear wave(ASW) generated by the mechanical movement of the needle. An acupuncture needle was driven by a piezoelectric transducer at100 Hz or below, and the ASW in human calf was imaged by magnetic resonance elastography. At the cell level, the ASW activatedintracellular Ca2+ transients and oscillations in fibroblasts and endothelial, ventricular myocytes and neuronal PC-12 cells along with frequencyamplitudetuning and memory capabilities. Monitoring in vivo mammalian experiments with ASW, enhancement of endorphin in blood plasmaand blocking by Gd3+ were observed; and increased Ca2+ fluorescence in mouse hind leg muscle was imaged by two-photon microscopy. In contrast with traditional acupuncture models,the signal source is derived from the total acoustic energy. ASW signaling makes use of the anisotropy of elasticity of tissuesas its waveguides for transmission and that cell activation is not based on the nervous system.