近日,，中國(guó)科學(xué)院北京基因組研究所章張研究員課題組與北京理工大學(xué),、中國(guó)林業(yè)科學(xué)研究院及華中農(nóng)業(yè)大學(xué)合作開(kāi)發(fā)完成RiceWiki數(shù)據(jù)庫(kù),。該數(shù)據(jù)庫(kù)是基于維基百科的水稻基因信息平臺(tái),，是可編輯且內(nèi)容公開(kāi)的公眾注釋系統(tǒng)。研究成果在Nucleic Acids Research雜志發(fā)表,。
水稻是人類(lèi)重要的糧食作物之一,，同時(shí)也是研究農(nóng)作物及其他相關(guān)植物的重要模式生物。因此,，水稻成為第一個(gè)全基因組測(cè)序的農(nóng)作物,。隨著水稻基因組學(xué)和轉(zhuǎn)錄組學(xué)研究的深入，先后出現(xiàn)了BGI-RIS,，TIGR,，RAP-DB和RGKbase等專(zhuān)業(yè)數(shù)據(jù)庫(kù)。這些數(shù)據(jù)庫(kù)多是依賴(lài)專(zhuān)業(yè)人員的編輯更新,，不僅費(fèi)時(shí)費(fèi)力,，而且成本也逐漸增加，導(dǎo)致其更新速度遠(yuǎn)遠(yuǎn)落后于水稻數(shù)據(jù)的指數(shù)增長(zhǎng),。RiceWiki數(shù)據(jù)庫(kù)的優(yōu)勢(shì)在于匯集整個(gè)水稻研究領(lǐng)域的科研人員的智慧和力量,，共同完善水稻基因的相關(guān)信息和數(shù)據(jù)更新，以期構(gòu)建一部水稻基因的百科全書(shū),。
目前,，RiceWiki已經(jīng)整合了兩個(gè)水稻栽培亞種的基因數(shù)據(jù)（O. sativa indica 93–11 和 O. sativa japonica Nipponbare），涵蓋66000多個(gè)水稻基因的相關(guān)信息,。水稻基因的原始資料主要來(lái)源于RefSeq （NCBI）,，Ensembl，RAP-DB和MSU Rice Genome Annotation Project,。每個(gè)水稻基因的資料由注釋信息,、研究該基因的相關(guān)實(shí)驗(yàn)室以及參考文獻(xiàn)和結(jié)構(gòu)信息構(gòu)成。
為了解決著作權(quán)的問(wèn)題,，RiceWiki還引入了作者獎(jiǎng)勵(lì)機(jī)制（AuthorReward）,，不僅可以評(píng)價(jià)基因注釋信息的質(zhì)量，還可以提高相關(guān)領(lǐng)域科研人員的參與度,。RiceWiki允許注冊(cè)用戶(hù)隨時(shí)創(chuàng)造,，更新和修改水稻基因信息，明顯的簡(jiǎn)化了資料收集,，分析和整理的過(guò)程,，以適應(yīng)生物學(xué)數(shù)據(jù)的爆炸式增長(zhǎng)模式。(生物谷Bioon.com)
生物谷推薦的英文摘要
Nucleic Acids Research doi: 10.1093/nar/gkt926
RiceWiki: a wiki-based database for community curation of rice genes
Zhang Zhang, Jian Sang, Lina Ma, Gang Wu, Hao Wu, Dawei Huang, Dong Zou, Siqi Liu, Ang Li, Lili Hao, Ming Tian, Chao Xu, Xumin Wang, Jiayan Wu, Jingfa Xiao, Lin Dai, Ling-Ling Chen, Songnian Hu and Jun Yu
Rice is the most important staple food for a large part of the world’s human population and also a key model organism for biological studies of crops as well as other related plants. Here we present RiceWiki (http://ricewiki.big.ac.cn), a wiki-based, publicly editable and open-content platform for community curation of rice genes. Most existing related biological databases are based on expert curation; with the exponentially exploding volume of rice knowledge and other relevant data, however, expert curation becomes increasingly laborious and time-consuming to keep knowledge up-to-date, accurate and comprehensive, struggling with the flood of data and requiring a large number of people getting involved in rice knowledge curation. Unlike extant relevant databases, RiceWiki features harnessing collective intelligence in community curation of rice genes, quantifying users' contributions in each curated gene and providing explicit authorship for each contributor in any given gene, with the aim to exploit the full potential of the scientific community for rice knowledge curation. Based on community curation, RiceWiki bears the potential to make it possible to build a rice encyclopedia by and for the scientific community that harnesses community intelligence for collaborative knowledge curation, covers all aspects of biological knowledge and keeps evolving with novel knowledge.
