近日,，中國科學院北京基因組研究所章張研究員課題組與北京理工大學、中國林業(yè)科學研究院及華中農業(yè)大學合作開發(fā)完成RiceWiki數據庫,。該數據庫是基于維基百科的水稻基因信息平臺,，是可編輯且內容公開的公眾注釋系統(tǒng)。研究成果在Nucleic Acids Research雜志發(fā)表,。
水稻是人類重要的糧食作物之一,，同時也是研究農作物及其他相關植物的重要模式生物。因此,，水稻成為第一個全基因組測序的農作物,。隨著水稻基因組學和轉錄組學研究的深入，先后出現了BGI-RIS,，TIGR,，RAP-DB和RGKbase等專業(yè)數據庫。這些數據庫多是依賴專業(yè)人員的編輯更新,，不僅費時費力,，而且成本也逐漸增加，導致其更新速度遠遠落后于水稻數據的指數增長,。RiceWiki數據庫的優(yōu)勢在于匯集整個水稻研究領域的科研人員的智慧和力量,，共同完善水稻基因的相關信息和數據更新,，以期構建一部水稻基因的百科全書。
目前,，RiceWiki已經整合了兩個水稻栽培亞種的基因數據（O. sativa indica 93–11 和 O. sativa japonica Nipponbare）,，涵蓋66000多個水稻基因的相關信息。水稻基因的原始資料主要來源于RefSeq （NCBI）,，Ensembl,，RAP-DB和MSU Rice Genome Annotation Project。每個水稻基因的資料由注釋信息,、研究該基因的相關實驗室以及參考文獻和結構信息構成,。
為了解決著作權的問題，RiceWiki還引入了作者獎勵機制（AuthorReward）,，不僅可以評價基因注釋信息的質量,，還可以提高相關領域科研人員的參與度。RiceWiki允許注冊用戶隨時創(chuàng)造,，更新和修改水稻基因信息,，明顯的簡化了資料收集，分析和整理的過程,，以適應生物學數據的爆炸式增長模式,。(生物谷Bioon.com)
生物谷推薦的英文摘要
Nucleic Acids Research doi: 10.1093/nar/gkt926
RiceWiki: a wiki-based database for community curation of rice genes
Zhang Zhang, Jian Sang, Lina Ma, Gang Wu, Hao Wu, Dawei Huang, Dong Zou, Siqi Liu, Ang Li, Lili Hao, Ming Tian, Chao Xu, Xumin Wang, Jiayan Wu, Jingfa Xiao, Lin Dai, Ling-Ling Chen, Songnian Hu and Jun Yu
Rice is the most important staple food for a large part of the world’s human population and also a key model organism for biological studies of crops as well as other related plants. Here we present RiceWiki (http://ricewiki.big.ac.cn), a wiki-based, publicly editable and open-content platform for community curation of rice genes. Most existing related biological databases are based on expert curation; with the exponentially exploding volume of rice knowledge and other relevant data, however, expert curation becomes increasingly laborious and time-consuming to keep knowledge up-to-date, accurate and comprehensive, struggling with the flood of data and requiring a large number of people getting involved in rice knowledge curation. Unlike extant relevant databases, RiceWiki features harnessing collective intelligence in community curation of rice genes, quantifying users' contributions in each curated gene and providing explicit authorship for each contributor in any given gene, with the aim to exploit the full potential of the scientific community for rice knowledge curation. Based on community curation, RiceWiki bears the potential to make it possible to build a rice encyclopedia by and for the scientific community that harnesses community intelligence for collaborative knowledge curation, covers all aspects of biological knowledge and keeps evolving with novel knowledge.
