加拿大安大略省圭爾夫大學(xué)的博士Peter Blecher以及他的父親一起在研制如何選擇奶牛的性別,,這項(xiàng)研究似乎可以允許農(nóng)民們使用人工受精的方式來(lái)選擇他們需要的奶?;蛘呤秦i的性別,。這將會(huì)對(duì)整個(gè)農(nóng)業(yè)造成極大的沖擊,。
但是Peter Blecher博士稱(chēng),沒(méi)有一個(gè)發(fā)瘋的科學(xué)家會(huì)使用基因技術(shù)來(lái)控制一種物種,,我們只是消除精子中我們不需要的性別,,我們并沒(méi)有對(duì)基因物質(zhì)進(jìn)行變動(dòng),最終用來(lái)受精的精子根本沒(méi)有被接觸。這個(gè)已經(jīng)申請(qǐng)了專(zhuān)利的技術(shù)就是使用一種可以聚集所有性別特定蛋白的抗體除去不需要的性別,。這樣可以提高奶農(nóng)們對(duì)奶牛性別的選擇性,。
Sex in the barnyard may never be the same.
A new process that appears to allow farmers to choose the sex of their cows and pigs in artificial insemination has the potential to revolutionize commercial agriculture.
But these aren't mad scientists using genetic technology to manipulate a species, stresses Dr. Peter Blecher, whose father Stan developed the process at the University of Guelph.
"We're just removing the sperm of the sex we don't want," said Blecher, founder of Sequent Biotechnologies, whose sperm-sexing technology inspired a recent friendly takeover by Microbix Biosystems Inc. (TSX:BMX).http://www.microbix.com/
"There's no manipulation of genetic material at all. The sperm that's used in the ultimate fertilization is untouched in any way."
The patented technology uses an antibody that can clump together all the sex-specific proteins in a semen sample and remove whatever sex is not wanted. That can mean major opportunities for producers who have only a 50 per cent chance of getting the sex of animal they want through artificial insemination.
The desire to pre-determine sex has been an issue for centuries.
"Since King Henry VIII started chopping the heads off his wives it's been something that's been a riddle to scientists," said Blecher. The British monarch executed two of his six wives, blaming them for not being able to produce male heirs.
But while baby determination is an ethical minefield among humans, it represents billions in increased efficiency to livestock producers around the world. For example, dairy farmers obviously prefer offspring to be milk-producing females.
Beef producers prefer male calves, which convert feed into lean muscle mass far faster than females. That can have huge implications to cattle ranchers who operated on razor-thin margins even before the mad cow crisis ravaged the industry. Female pigs are easier to control.
"Look at any major global business that's operating on a 50 per cent inefficiency," said Blecher. "That would be considered disastrous by any standards."
Dairy operator Michael Hall says the technology, if proven, would be a natural evolution of the artificial insemination industry.
"If I could pick the top 25 per cent of cows in my barn and make sure they have heifers every year, that would be a significant production advantage," said Hall, a director with the Dairy Farmers of Canada, who runs an operation south of Ottawa.
Semen sexing has been available in the United States and Europe for several years, but there has been limited uptake across the industry because it is expensive and invasive, says reproduction physiologist Michael Dyck.
"Artificial insemination has revolutionized the dairy industry," said Dyck, who teaches animal science at the University of Alberta and focused research on embryonic transfers in swine.
"This could be a very nice add-on to that."
Further testing and field trials of the technology will be done over the next three years by Microbix, which specializes in the development of biotherapeutic drugs, vaccines, and infectious disease diagnostics. The company expects a market launch in 2008.
Dyck doubts there will be many ethical concerns raised.
"This technology has been developed in parallel with things like cloning or trans-genesis," he said. "So when you put this alongside that kind of manipulation, the animal rights activists are probably going to lean more toward (protesting) genetic manipulation."
And while producers across Canada have embraced artificial insemination, many cattle are still reproducing the old fashioned way as Nature intended.
"There's still a large percentage of herds that . . . still use a barnyard bull," said Hall.